This study examined workplace collaboration and its relationship with enterprise success in the manufacturing sector of Nigerian economy with special emphasis on the south -south region which includes only Bayelsa and Rivers State.  The data is obtained using structured questionnaires administered to an accessible population of 75 top and middle level managers within five (5) selected manufacturing organizations, recognized and registered with the manufacturers association of Nigeria (MAN) Rivers/Bayelsa State branch and operating geographically within River State in which the study was domiciled. The findings of this  study “workplace collaboration” proves that the success of an organization depends on how they are able to work in team to produce a valuable product, their communication level with their customers, their relationship with other organizations to perform better and how they relate with the host community and their immediate environment. Therefore, management of the manufacturing sector in the Nigeria economy should encourage community collaboration to bridge the hostile gap between them and the environment. Social network collaboration is also critical for the formation of a broad-based followership and interdependence among all actors. Team and enterprise collaborations as well are essential for building a united workforce that ultimately results in organizational productivity.