Tayyar CANTÜRK, Levent YILDIZ, Asiye YILDIZ, Oğuz AYDIN, Ahmet Yaşar TURANLI

The acanthosis nigricans associated with gastric adenocarcinoma and neurofibromatosis

Akantozis Nigrikans ile Birlikte Gastrik Adenokarsinom ve Nörofibromatozis internal malignité ve nörofibromatozis ile birlikte akantozis nigrikans olgusunu sunuyoruz. Kaşıntı ve akantozis nigrikansı çağrıştıran aksiller ve inguinal diskolorasyon yakınmaları ile başvuran 45 yaşındaki erkek hastada tanı deri biyopsisi ile doğrulandı. Tomografik, endoskopik ve histopatolojik araştırmalarda mide korpusunda ileri evrede, az diferansiye adenokarsinom saptandı.Gövdede "café au lait" lekeleri ve deri renginde, pedinküle yumuşak nodüller mevcuttu. Histopatolojik olarak nörofibrom tanısı nodüllerin birinin eksizyonu ile doğrulandı.

Anahtar Kelimeler:

Akantozis nikrikans, Mide neoplazmları, Adenokarsinom, Nörofibromatözler, Orta Yaş, Erkek

Akantozis nigrikans ile birlikte gastrik adenokarsinom ve nörofibromatozis

We presented a case of acanthosis nigricans who exhibited an internal malignancy and neurofibrornatosis. The patient who is 45 years old had pruritus and axillary and inguinal discoloration resembling Acanthosis nigricans. The diagnosis was confirmed by the biopsy of the skin. The tomographic, endoscopie, and histopathologic singular revealed a poorly differentiated gastric carcinoma of the corpus which was at advanced stage. There were macules in close similarity with café au lait macules, and skin-colored, pedinculated soft nodules. The histopathologic diagnosis of neuroflbrorna was confirmed by the excision of one of the nodules.

Keywords:

Acanthosis Nigricans, Stomach Neoplasms, Adenocarcinoma, Neurofibromatoses, Middle Age, Male,

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