Ketojenik Diyet ve Duygudurum Bozukluğu

Ketojenik diyetin, depresyon ve duygudurum bozuklukları tedavisinde etkinliğini gösteren çalışmalar, tamamen sağlıklı bireylerin ketojenik diyet sonrası, duygudurum değişikliği ve bozukluğu oluşabileceği ihtimalini ve araştırılması gerektiği gerçeğini akıllara getirmektedir. Bu çalışmada, literatürde ilk kez, ketojenik diyet uygulayan ve psikiyatrik hastalığı olmayan bireylerde duygudurum bozuklukları araştırılmıştır. Tıbbi amaç olmaksızın ketojenik diyet uygulayan 18-65 yaş arası erkek ve kadın gönüllüler çalışmaya alınarak, web tabanlı anket sorularını cevaplamaları istenmiştir. Duygudurum bozukluğunun taranması için “Duygudurum Bozukluğu Ölçeği” uygulanmıştır. Psikiyatrik herhangi bir hastalığı olmayan 60 katılımcı çalışmaya dâhil edilmiştir. Katılımcıların ketojenik diyet yapma süreleri ortalama 5.7 aydı. Katılımcılarda duygudurum bozukluğu, genel popülasyonda beklenenden daha yüksek oranda, %26.7 oranında tespit edilmiştir. Duygudurum bozukluğu ile katılımcıların yaşı arasında istatistiksel anlamlı ilişki varken (p=0.029), duygudurum bozukluğu ile cinsiyet, beden kitle endeksi, obezite sınıflandırması ve ketojenik diyet süreleri arasında anlamlı ilişki bulunmamıştır (p>0.05). Duygudurum bozukluğu pozitif saptanan bireyler, daha konuşkan, kendine güvenen, daha az uyuyan, düşünceleri daha hızlı, daha kolay dikkati dağılan, daha sosyal, cinsellikle daha fazla ilgilenen ve daha fazla para harcayan kişiler oldukları tespit edildi ve istatistiksel olarak bu durumları anlamlı bulundu (p<0.05). Çalışmamızda, ketojenik diyet uygulanan bireylerde duygudurum bozukluğu yüksek bir oranda, %26.7 oranında saptanmıştır. Bu sonuç, ketojenik diyet uygulanan bireylerde duygudurum bozukluğunun taranmasını ve riskli bireylerde ketojenik diyet uygularken dikkat edilmesi gerektiğini ortaya koymaktadır.

Anahtar Kelimeler:

Bipolar Bozukluk, Duygudurum Bozukluğu, Ketojenik Diyet, Ölçek

Ketogenic Diet and Mood Disorder

Studies investigating the effectiveness of the ketogenic diet in the treatment of depression and mood disorders bring to mind the possibility that a healthy individual may develop a mood disorder after a ketogenic diet. In this study, for the first time in the literature, it was aimed to investigate mood disorders in psychiatrically healthy individuals who are following a ketogenic diet. Volunteers between the ages of 18-65, who went on a ketogenic diet without medical purposes, were included in the study and asked to answer web-based questions including the “Mood Disorder Questionnaire”. Sixty participants, who did not have any known psychiatric illnesses, and who did not use any psychiatric medications were included. The mean duration of the participants' ketogenic diet was 5.7 months. The ratio of the mood disorder was found to be 26.7%. A statistical difference was found between mood disorder and age (p=0.029); but no significance was detected between mood disorder and gender, body mass index, obesity and diet durations. Those with positive mood disorders were more active, more social and talkative, more self-confident, less sleepy, more interested in sexuality, spent more money, easily distracted, thoughts were faster in their minds and all these differences were statistically significant (p<0.05). The present study found the rate of mood disorders to be 26.7% in individuals who were following a ketogenic diet. This reveals the necessity of screening for mood disorders in individuals on ketogenic diet and the necessity of avoiding ketogenic diet in patients at risk.

Keywords:

Bipolar Disorder, Mood Disorder, Ketogenic Diet, Questionnaire,

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