Nosocomial Infections and Cases of Sphingomonas Paucimobilis

Sphingomonas paucimobilis (S. paucimobilis), especially in patients with immune suppressive and very rare in healthy people, attracted attention recently, causing nosocomial infections, is a gram-negative, aerobic bacillus. This bacterial nosocomial infection in our hospital as a first six-month period, six times was isolated from five patients. These five patients were acute peritonitis, vaginal cuff, surgical field, soft tissue and bloodstream infection. The identification of microbiological methods known to S. paucimobilis was examined by the antibiotic sensitivity disk diffusion test. Antibiotic sensitivity of the isolated bacteria were the same. From the environment and environment cultures S. paucimobilis was isolated once from the use water as a hospital infection effect. It was realized that the chlorination of hospital waters was inadequate during that period. Our hospital was thought to have a small epidemic. In conclusion, S. paucimobilis has recently been investigated in the context of literature with the belief that a new nosocomial infection will be affected.

Nosokomiyal Enfeksiyonlar ve Sphingomonas Paucimobilis: Olguların Sunumu

Sphingomonas paucimobilis (S. paucimobilis) özellikle immünsüpresif hastalarda ve sağlıklı insanlarda oldukça nadir görülen, son zamanlarda dikkati çeken, nozokomiyal enfeksiyonlara neden olan, gram-negatif, aerobik bir basildir. Bu bakteri hastanemizde ilk altı aylık bir süreç içersinde nozokomiyal enfeksiyon etkeni olarak, beş hastadan altı kez izole edildi. Toplam beş hasta; akut peritonit, vaginal cuff, cerrahi alan, yumuşak doku ve kan yolu enfeksiyonu idi. S. paucimobilis’in identifikasyonu bilinen mikrobiyolojik yöntemlerle, antibiyotik duyarlılığı ise disk difüzyon testi ile incelendi. İzole edilen bakterilerin antibiyotik duyarlılığı aynı idi. Yapılan çevre ve ortam kültürlerinden S. paucimobilis hastane enfeksiyon etkeni olarak bir kez kullanım suyundan izole edildi. O süreç içersinde hastane sularının klorlamasının yetersiz olduğu fark edildi. Hastanemizde küçük bir epidemi olduğu düşünüldü. Sonuçta S. paucimobilis son zamanlarda yeni bir nozokomiyal enfeksiyon etkeni olacağı düşünülerek literatür eşliğinde olgularla irdelendi.

___

Perl TM. Surveillance, reporting, and the use of computers. In: Wenzel RP. ed. Prevention and Control of Nosocomial Infections. Second edition, Williams & Wilkins, Baltimore, Maryland, 1993, p.139-76.

Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections. 1988. Am J Infect Control 1988; 16: 128-40.

Ryan MP, Adley CC. Sphingomonas paucimobilis: a persistent Gram-negative nosocomial infectious organism. J Hosp Infect. 2010 ; 75 : 153-57.

Lin JN, Lai CH, Chen YH, et al. Sphingomonas paucimobilis bacteremia in humans: 16 case reports and a literature review. (JMII) Journal of Microbiology Immunology and Infection 2010; 43 : 35-42.

Maragakis L, Chalwarith R, Srivinivasan A, Torriani F et all. Sphingomonas paucimobilis bloodstream infections associated with contaminated intravenous fentanyl. Emerging Infect Dis 2009; 1 : 12-18.

Dervisoglu E, Meric M, Kalender B, SEngul E. Sphingomonas paucimobilis peritonitis: a case report and literature review. Peritoneal Dialysis International 2008; 8: 547-50.

Casadewall A, Freundlich LF, Profiski L. Septic shock caused by Pseudomonas paucimobilis. Clin Infect Dis 1992; 14: 784.

Tambawala AQ, Hamid S, Khan I, Ali A. Continous ambulatory peritoneal dialysis (CAPD) associated in a child : A rare case of peritonitis caused by Sphingomonous paucimobilis. J Pak Med Assos 2011; 6: 178-80.

Willke A, Kolayli F, Yavuz S, Vahaboglu H. Water-borne Sphingomonas paucimobilis epidemic in an intensive care unit. J Infect. 2009 ; 58: 253-55.

Bulut C, Yetkin MA, Koruk ST, Erdinç FS, Karakoç EA. A rare cause of nosocomial bacteremia: Sphingomonas paucimobilis. Mikrobiyol Bul. 2008; 42: 685-88.

Cheong HS, Wi YM, Moon SY, Kang CI, Son JS, Ko KS, Chung DR, Lee NY, Song JH, Peck KR. Clinical features and treatment outcomes of infections caused by Sphingomonas paucimobilis. Infect Control Hosp Epidemiol. 2008; 29: 990-92.

Toh HS, Tay HT, Kuar WK, Weng TC, Tang HJ, Tan CK. Risk factors associated with Sphingomonas paucimobilis infection. J Microbiol Immunol Infect 2011; 44: 2890-95.

Kilic A, Senses Z, Kurekci AE, Aydogan H, Sener K, Kismet E, Basustaoglu AC. Nosocomial outbreak of Sphingomonas paucimobilis bacteremia in a hemato/oncology unit. Jpn J Infect Dis. 2007; 60: 394-96.

Ensminger SA, Wright RS, Baddour LM, Afessa B. Suspected ventilator-associated pneumonia in cardiac patients admitted to the coronary care unit. Mayo Clin Proc. 2006; 81: 32-5.

Källman O, Lundberg C, Wretlind B, Ortqvist A. Rare bacteria species found in wounds of tsunami patients. Predominance of gram-negative rods, increased antibiotic resistance. Lakartidningen. 2005; 102: 3660-65.

Perola O, Nousiainen T, Suomalainen S, Aukee S, Kärkkäinen UM, Kauppinen J, Ojanen T, Katila ML. Recurrent Sphingomonas paucimobilis -bacteraemia associated with a multi-bacterial water-borne epidemic among neutropenic patients. J Hosp Infect. 2002; 50: 196-201.

Hsueh PR, Teng LJ, Yang PC, Chen YC, Pan HJ, Ho SW, Luh KT. Nosocomial infections caused by Sphingomonas paucimobilis:clinical features and microbiological characteristics. Clin Infect Dis. 1998; 26: 676-81.

Nandy S, Dudeja M, Das AK, Tiwari R. Community Acquired Bacteremia by Sphingomonas paucimobilis: Two Rare Case Reports. J Clin Diagn Res. 2013; 7: 2947-79.

Glupczynski Y, Hansen W, Dratwa M, Tielemans C, Wens R, Collart F, Yourassowsky E: Pseudomonas paucimobilis peritonitis in patients treated by peritoneal dialysis. J Clin Microbiol 1984; 20: 1225-26.

Turhanoğlu NM, Bilman FB, Sekiz yıllık dönemde Sphingomonas paucimobilis infeksiyonları. Flora 2013; 16: 113-118.

Bayram N, Devrim İ, Apa H, Gulfidan G, Turkyılmaz HN, Gunay İ. Spingomonas paucimobilis infections in children:24 case perorts. Mediterr J Hematol Infect Dis. 2013; 5: e2013040.

Kıvrak EE, Taşbakan MI, Öztürk AM, ve ark. Nadir bir cerrahi alan infeksiyonu etkeni: Sphingomonas paucimobilis (olgu sunumu). ANKEM Derg 2010; 24: 234-36.
Meandros Medical And Dental Journal-Cover
  • ISSN: 2149-9063
  • Başlangıç: 2000
  • Yayıncı: Erkan Mor
Sayıdaki Diğer Makaleler

A Rare Cause of Paresthesia: Hypophosphatemia

Zeynep ÖZÖZEN AYAS, Ruhsen ÖNCEL ÖCAL, Ayhan BÖLÜK

Effect of Poly(Methyl Vinyl Ether-comaleicAnhydride) Copolymer on Bond Strength of Experimental Dental Adhesive

Özge ÇELİKSÖZ, ÖZGÜR IRMAK, Zeynep DİKMEN, Batu Can YAMAN, VURAL BÜTÜN, Füsun ÖZER

Oral Precancerous Lesions in Childhood: Attention to the Pediatricians and Pediatric Dentists

ŞAZİYE SARI, İlhan KARA, Akif DEMİREL

Çeşitli İrrigasyon Protokollerinin İkili ve Üçlü Antibiyotik Patlarını Uzaklaştırma Etkinliklerinin Değerlendirilmesi

Evren SARIYILMAZ, Cangül KESKİN

The Comparison of Different Surface Preparation Methods in Terms of Shear Bond Strength of Tri-ceram Porcelaintitanium Alloy

Berivan Dündar YILMAZ, Ayşe MEŞE, Eylem KAYA

Management of Diffuse Abdominal Cellulitis After Cesarean Section

Sümeyra Nergiz AVCIOĞLU, Emre ZAFER, Sündüz Özlem ALTINKAYA, Selda DEMİRCAN SEZER, Hasan YÜKSEL

Patient-specific Root-analogue Immediate Titanium Premolar Dental Implants: Prospective Evaluation of Fifteen Patients with One-year Follow-up

Ahmet Emin DEMİRBAŞ, Emine Fulya AKKOYUN, Hasan Önder GÜMÜŞ, Banu Arzu ALKAN, Alper ALKAN

Yoğun Pestisite Maruz Kalan Sera İşçilerinin Kanlarındaki Ksantin Oksidaz, Nitrik Oksit ve Arilesteraz Seviyelerinin ve Beslenme Alışkanlıklarının Belirlenmesi

Erdoğan KÜÇÜKÖNER, Serdal ÖĞÜT, Fatih GÜLTEKİN, Ebru ÖNEM

Miyotonik Distrofi

Zeliha ÜNLÜ

Evaluation of Double and Triple Antibiotic Paste Removal Efficiency of Various Irrigation Protocols

Evren SARIYILMAZ, Cangül KESKİN