Nesrin SARIMAN, Ender LEVENT, Akın Cem SOYLU, Şirin YURTLU

“Orta ve Ağır Obstrüktif Uyku Apne Sendromu OUAS Olgularında PAP Positive Airway Pressure Titrasyonuna Objektif ve Subjektif Yanıtın Değerlendirilmesi”

Amaç: Bu çalışmada orta ve ağır obstrüktif uyku apne sendromu OUAS tanısı alıp PAP Positive Airway Pressure titrasyonuna alınan olguların, titrasyon gecesinde elde edilen objektif ve subjektif yanıtları ile ilk gece yapılan polisomnografi testi yanıtları karşılaştırılmıştır. Yöntem: Maltepe Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı Uyku Bozuklukları Laboratuvarında Mayıs 2008-Mayıs 2009 tarihleri arasında orta ve ağır OUAS tanısı almış olan erişkin, yaş ortalaması 54 ± 11 yıl 32-73 yaş arası , 10 kadın ve 26 erkek toplam 36 olgu çalışmaya alındı. Uyku laboratuvarında polisomnografi testine alınan tüm olgulara testin sonlandığı sabah uygulanan anket formundaki bilgiler kullanılarak, subjektif yanıtlar, polisomnografi kayıtlarındaki verilerden ise objektif yanıtlar elde edildi. İlk test gecesi, titrasyon gecesi ile objektif ve subjektif veriler kullanılarak karşılaştırıldı. Subjektif verilerin değerlendirilmesinde vizüel analog skorlama VAS yöntemi kullanıldı. Bulgular: İlk gece PSG sonuçları titrasyon gecesi sonuçları ile karşılaştırıldığında; toplam uyku süresi, REM periyodu, solunumsal arousallar, bazal oksijen satürasyonu ve en düşük oksijen satürasyonu değerlerinde; hastaların subjektif yanıtları değerlendirildiğinde ise, titrasyon gecesinde ilk gece yanıtlarına göre her zamanki uykusu ile karşılaştırıldığında uyku memnuniyeti algısında, dinlenmiş ve uykusunu almış olarak uyanma algısında olumlu yönde anlamlı farklılıklar elde edildi p

Anahtar Kelimeler:

obstrüktif uyku apne sendromu, PAP titrasyonu, CPAP-BIPAP yanıtı

“Objective and Subjective Responses to PAP Positive Airway Titration in Moderate and Severe Obstructive Sleep Apnea Syndrome”

Aim: The purpose of this study was to compare the objective and subjective responses of moderate and severe OSAS patients to the fi rst night polysomnography and PAP titration test. Materials and methods: Ten female, 26 male a total 36 patients with a mean age of 54 ± 11 years range 32-73 and polysomnographically verifi ed as moderate and severe OSAS in Sleep Resarch Laboratory of Chest Diseases Department at Maltepe University Hospital between May 2008-May 2009 were included in the study. Subjective responses were obtained from the questionnaire applied on the morning after the fi rst polysomnography and PAP titration nights. Objective responses were also achieved from the polysomnography records of both test nights. We compared the objective and subjective responses of patients to both tests. Diff erences between the two tests nights were evaulated seperately. Visual analog scoring VAS was used to evaluate subjective values. Results: When we compared the responses to the fi rst night polysomnography and PAP titration we found statistically signifi cant diff erences betwen the values of total sleep time, REM sleep, respiratoy arousals, basal oxygen saturation and minimal avarage oxygen saturation. Subjective responses revealed that there were diff erences between the titration night and fi rst polysomnography night suggesting positive changes in terms of patient satisfaction and statistically signifi cant diff erences were achieved between the two nights regarding patient satisfaction of sleep quality and feeling of awaked rested in the morning p

Keywords:

obstructive sleep apnea syndrome, PAP titration, response to CPAP- BIPAP therapy,

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