Eda AYDIN, Aykut İKİNCİOĞULLARI, Süleyman Emre KARAKURT, Nurcan KUM, Zekiye ORHAN, HACI HÜSEYİN DERE

Parotis Bezinin Nadir Görülen Malign Tümörü Lenfoepitelyal Karsinom: Olgu Sunumu

Tükürük bezi malign tümörleri tüm baş boyun malign tümörlerinin %3’ünü oluşturur. Görece az görülen bu tümörler içerisinde de lenfoepitelyal karsinom son derece nadir karşılaşılan histolojideki tümörlerdir ve Epstein-Barr Virüs (EBV) pozitifliği ile ilişkisi bulunmaktadır. Bu olgu sunumunda sol parotis bezinde lenfoepitelyal karsinoma sahip 72 yaşındaki erkek hastaya tanı ve tedavi yaklaşımımızı literatür eşliğinde sunmayı amaçladık.

A Rare Malign Tumor Of The Parotid Gland Lymphoepithelial Carcinoma: Case Report

Malign salivary gland tumors constitues %3 of all kinds of malign head and neck tumors. Among these tumors, which are relatively rare, lymphoepithelial carcinoma is the one that is extremely rare in histology and it has relation with Epstein-Barr Virus (EBV) positivity. In this presentation, we aim to present our diagnosis and treatment approach to a72 year-old male patient who has parotid lymphoepithelial carcinoma with a review of the literature.

PDF

___

Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 1986;8:177-184.
Tang CG, Schmidtknecht TM, Tang GY, et al. Lymphoepithelial carcinoma: a case of a rare parotid gland tumor. Perm J 2012;16(3):60–2.
Li F, Zhu G, Wang Y, et al. A clinical analysis of 37 cases with lymphoepithelial carcinoma of the major salivary gland treated by surgical resection and postoperative radiotherapy: a single institution study. MedOncol 2014;31:957.
Kim YJ, Hong HS, Jeong SH, et al. Lymphoepithelial carcinoma of the salivary glands. Medicine 2017 Feb;96(7):e6115
Maeda H, Yamashiro T, Yamashita Y, et al. Lymphoepithelial carcinoma in parotid gland related to EBV infection: A case report. Auris Nasus Larynx 2017 [Epub ahead of print]
Hamilton-Dutoit SJ, Therkildsen MH, Nielsen NH, et al. Undifferentiated carcinoma of the salivary gland in Greenlandic Eskimos: demonstration of Epstein-Barrvirus DNA by in situ nucleic acid hybridization. Hum Pathol 1991;22:811-5.
Squllaci S. Lymphoepithelioma-Like Carcinoma (LELC) of Salivary Gland Associated with Epstein-BarrVirus in a North Italian Woman. Report of a New Case and Review of the Literature. In: Constantine SU, editor. New Developments in Epstein-BarrVirusResearch. New York: Nova SciencePublishers; 2006. p. 233-60.
Özbey AO, Bora F, Kutluhan A, et al. Parotid kitlelerinin değerlendirilmesinde ince iğne aspirasyon biyopsisi ile histopatolojinin karşılaştırılması. Kafkas J Med Sci 2014 4(2):57–61.
Sone M, Nakashima T, Nagasaka T, et al. Lymphoepithelioma-like carcinoma of the larynx associated with an Epstein-Barr viral infection. OtolaryngolHeadNeckSurg 1998; 119: 134-7.
Lü BJ, Zhu J, Gao L, et al. Diagnostic accuracy and pitfalls in fine needle aspiration cytology of salivary glands: a study of 113 cases. Zhonghua Bing Li Xue Za Zhi. 2005 Nov;34(11):706-10.
[Diagnostic accuracy and pitfalls in fine needle aspiration cytology of salivary glands: a study of 113 cases]. Zhonghua Bing Li Xue Za Zhi 2005;34(11):706-10.
Abdulla AK, Mian MY. Lymphoepithelial carcinoma of salivary glands. HeadNeck. 1996 ;18:577-81.