KRONİK OBSTRÜKTİF AKCİĞER HASTALARINDA ANKSİYETE VE DEPRESYONUN BİLİŞSEL DURUMA ETKİSİ

Giriş: Bu çalışma Kronik Obstrüktif Akciğer Hastalığı (KOAH) hastalarında anksiyete ve depresyonun bilişsel duruma etkisini belirlemek amacıyla tanımlayıcı olarak yapılmıştır. Gereç ve Yöntem: Çalışmanın örneklemini Göğüs Hastalıkları hastanesinde tedavi gören 80 hasta oluşturmuştur. Verilerin toplanmasında Hastane Anksiyete ve Depresyon ölçeği (HADÖ) ve Standardize Mini Mental değerlendirme testi (SMMT-E) kullanılmıştır. Bulgular: Çalışmaya katılan hastaların yaş ortalaması 67.73 (10.33) yıldır. HADÖ anksiyete puanı ortalaması 10.44 (2.38), HADÖ depresyon puanı ortalaması 9.98 (2.23) ve SMMT-E puanı 14.68 (2.66)'dır. HADÖ anksiyete skoru ile SMMT-E arasında negatif yönde ilişki saptanmıştır (r=-0.29, p= 0.01). Çoklu regresyon analizinde sigara kullanma durumu ve HADÖ-anksiyetenin SMMTE'yi ne ölçüde belirlediği değerlendirilmiş ve R ve R2 faktörleri sırasıyla 0.445 ve 0,19 olarak bulunmuştur Ayrıca SMMT-E'deki toplam varyansın %19'unun bu değişkenlerce açıklandığı görülmüştür (y=19.876-0.320*X1-1.187*X2). Sonuç: KOAH hastalarında anksiyete düzeyinin SMMT-E'yi etkilediği ve bu nedenle KOAH hastalarında anksiyetenin azaltılmasına yönelik önlemlerin alınması önerilmiştir.

The Effect of Anxiety-Depression on the Cognitive Status in Patients with Chronic Obstructive Diseases

Introduction: This descriptive study was to performed on the effect of anxiety-depression on the cognitive status in patients with chronic obstructive diseases (COPD). Material and Methods: The study was conducted with 80 COPD patients treated at Lung diseases hospital inpatient departments. Subjects were surveyed using Hospital Anxiety and depression scale (HADS) and Standardize Mini Mental State Examination (SMMT-E). Results: The mean age patients was 67.73 (10.33) years. HADS anxiety was 10.44 (2.38), HADS depression was 9.98 (2.23), SMMT-E was 14.68. According to the results of multipl regression analysis, variables such as smoking status and HADS-anxiety predict the SMMT-E, the R and R2 factors were 0.445 and 0.19, respectively. Also it was observed that 19% of the total variance of the SMMT-E was explained by the above variables (y=19.876-0.320*X1-1.187*X2). Conclusion: It was determined that anxiety effects to SMMT-E and therefore it could be advised to taking measures to reduce anxiety COPD patients.

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  • Mannino DM, Buist AS. Global burden of COPD: risk factors, prevalence, and future trends. Lancet. 2007; 370:765-73.
  • Dodd JW, Getov SV, Jones PW. Cognitive functions in COPD. Eur Respir J. 2010; 35: 913-22. doi: 10.1183/09031936.00125109.
  • Etnier J, Johnston R, Dagenbach D, Pollard RJ, Rejeski WJ, Berry M. The relationships among pulmonary function, aerobic fitness, and cognitive functioning in older COPD patients. Chest. 1999; 116(4): 953-60.
  • Dodd JW, Charlton RA, van den Broek MD, Jones PW. Cognitive Dysfunction in Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD). Chest. 2013; 144(1): 119-27. doi: 10.1378/chest.12-2099.
  • Hung WW, Wisnivesky JP, Siu AL, Ross JS. Cognitive decline among patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009; 180(2): 134-7. doi: 10.1164/rccm.200902-0276OC.
  • Isoaho R, Puolijoki H, Huhti E, Laippala P, Kivela SL. Chronic obstructive pulmonary disease and cognitive impairment in the elderly. Int Psychogeriatr. 1996; 8:113-25.
  • Kim HFS, Kunik ME, Molinari VA, et al. Functional impairment in COPD patients The impact of anxiety and depression. Psychosomatics. 2000; 41: 465-71.
  • Mikkelsen RL, Middelboe T, Pisinger C, Stage KB. Anxiety and depression in patients with chronic obstructive pulmonary disease (COPD). A review. Nord J Psychiatry 2004; 58: 66-70.
  • Aydemir Ö. Hastane Anksiyete ve Depresyon Ölçeği Türkçe formunun geçerlilik ve güvenilirlik çalışması. Türk Psikiyatri Dergisi. 1997; 8: 280-7.
  • Güngen C, Ertan T, Eker E. Standardize Mini Mental Test'in Türk toplumunda hafif demans tanısında geçerlik ve güvenirliği. Türk Psikiyatri Dergisi. 2002; 13(4): 273-81.
  • Ertan T, Eker E, Güngen C ve ark. The Standardized Mini Mental State Examination for illeterate Turkish elderly population. 2th International Symphosium on Neuropsychological Assesment of Mental and Behavioral Disorders, August 1999, Kirazlıyayla, Bursa, Turkey. 1999.
  • Anar C, Tatar D, Gediktaş E ve ark. Frequency of Anxiety-Depression Among Chronic Obstructive Pulmonary Disease (Copd) Patients Who Use Home Oxygen Therapy. İzmir Göğüs Hastanesi Derg. 2012; 24 (2): 83-9.
  • Afşar BB, Yalçınsoy M, Yakar Hİ ve ark. Evaluation of individuals with Chronic Obstructive Pulmonary Disease in terms of disability, anxiety and depression, Cumhuriyet Medical J. 2012; 34: 260-7.
  • Tutuk SPM, Altun ÖŞ. Determination of Hospital Anxiety and Depression Levels of Patients Admitted to Hospitals with COPD Diagnosis. Sted. 2014, 23 (6): 216-24.
  • Puhan MA, Frey M, Büchi S, Schünemann HJ. The minimal important difference of thehospital anxiety and depression scale in patientswith chronic obstructive pulmonary disease. Health Qual Life Outcomes. 2008 Jul 2; 6: 46. doi: 10.1186/1477- 7525-6-46.
  • Asnaashari AM, Talaei A, Haghigh B. Evaluation of psychological status in patients with asthma and COPD. Iran J Allergy Asthma Immunol. 2012; 11(1): 65-71. doi: 011.01/ijaai.6571.
  • Liesker JJ, Postma DS, Beukema RJ, et al. Cognitive performance in patients with COPD. Respir Med. 2004; 98(4): 351-6.
  • Büyükkoyuncu N. Kronik obstruktif akciğer hastalığı olan hastalarda kognitif fonksiyonların değerlendirilmesi. Trakya Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı, Uzmanlık Tezi, 2008.
  • Dal Negro RW, Bonadiman L, Bricolo FP, Tognella S, Turco P. Cognitive dysfunction in severe chronic obstructive pulmonary disease (COPD) with or without Long-Term Oxygen Therapy (LTOT). Multidiscip Respir Med. 2015 19; 10(1): 17. doi: 10.1186/s40248-015-0013-4.
  • Federman AD, Wolf MS, Sheng T, O'Conor R, Martynenko M, Wisnivesky J. Diminished Cognitive FunctionAmong Chronic Obstructive Pulmonary Disease Patients During Periods of Acute Illness Exacerbation. J Gerontol A Biol Sci Med Sci. 2016; 71(2) 279-80. doi: 10.1093/gerona/glv200.
  • Dulohery MM, Schroeder DR, Benzo RP. Cognitive function and living situation in COPD: is there a relationship with self-management and quality of life? Int J Chron Obstruct Pulmon Dis. 2015; 10: 1883-9. doi: 10.2147/COPD.S88035
  • Ozyemisci-Taskiran O, Bozkurt SO, Kokturk N, Karatas GK. Is there any association between cognitive status and functional capacity during exacerbation of chronic obstructive pulmonary disease? Chron Respir Dis. 2015; 12(3): 247-55. doi: 10.1177/1479972315589748. Epub 2015 Jun 11.
  • Wang CC, Lu TH, Liao WC, et al. Cigarette smoking and cognitive impairment: a 10-year cohort study in Taiwan. Arch Gerontol Geriatr. 2010; 51: 143-8. doi: 10.1016/j.archger.2009.09.041.
  • Moussas G, Tselebis A, Karkanias A, et al. A comparative study of anxiety and depression in patients with bronchial asthma, chronic obstructive pulmonary disease and tuberculosis in a general hospital of chest diseases. Ann Gen Psychiatry. 2008; 7:7.
  • Mah L, Szabuniewicz C, Fiocco AJ. Can anxiety damage the brain? Curr Opin Psychiatry. 2016; 29(1): 56-63.
Kırıkkale Üniversitesi Tıp Fakültesi Dergisi-Cover
  • ISSN: 2148-9645
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1999
  • Yayıncı: KIRIKKALE ÜNİVERSİTESİ KÜTÜPHANE VE DOKÜMANTASYON BAŞKANLIĞI