Bladder Sarcomatoid Carcinoma in an Adolescent: 10-Year Survival After Aggressive Surgical Management

Bladder cancer is a rare entity in the pediatric population. Sarcomatoid carcinoma is considered a variant histology of bladder urothelial carcinoma and is exceedingly unusual in children. We present a case of a 14-year-old black female who presented to the pediatric urology clinic with hematuria. Her history was notable for acute lymphocytic leukemia treated with cyclophosphamide, which had been in remission for four years. Subsequent workup demonstrated a large, complex bladder mass, consistent with sarcomatoid carcinoma following transurethral resection. She underwent a radical cystectomy with bilateral pelvic lymphadenectomy and ileal conduit and remains disease free 10 years after diagnosis.

Bir Ergende Mesane Sarkomatoid Karsinomu: Agresif Cerrahi Yönetimi Sonrası 10 Yıllık Sağkalım

Pediatrik popülasyonda mesane kanseri nadir bir oluşumdur. Sarkomatoid karsinomda, mesane üroteliyal karsinomunun değişken histolojisi dikkate alınır ve çocuklarda son derece olağan dışıdır. Burada, pediatrik üroloji kliniğine hematuri ile başvurmuş 14 yaşındaki siyahi bir kadın olgusu sunulmuştur. Dört yıldır remisyonda olan, siklofosfamid ile tedavi edilen akut lenfositik lösemi için olgunun öyküsü kayda değerdi. Transüretral rezeksiyonu takiben yapılan tetkikler, sarkomatid karsinomu ile birbirini tutan büyük bir kompleks mesane kitlesini kanıtlamıştır. Hastaya, radikal sistektomi ile iki taraflı pelvik lenfadenektomi ve ileal konduit uygulanmıştır, tanıdan sonra 10 yıldır hastalıksız bir şekilde hayatını sürdürmektedir.

Kaynakça

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