Objective: This hospital-based retrospective cohort study was undertaken with a view to determine the epidemiological trendof measles in Lagos State, NigeriaMethods: Medical records of clinically diagnosed measles patients from nine referral public hospitals in Lagos State between1998 and 2007 were retrieved, transcribed and reviewed. Data were analyzed using standard methods.Results: A total of 35,500 clinically confirmed cases and 835 deaths (case fatality rate = 2.35%/10 years) were recorded. Themean incidence was estimated at 19 cases per 100,000 population/year. A consistent seasonality pattern of measles wasobserved for the study period. The under-fives accounted for the highest reported cases (76.30%) while, the under-1 yearrecorded highest mortality (53.8%). Notable shift of measles vulnerability from under-1year to under-fives was observed. Althoughthere was significant difference between cases and deaths among the age groups (p<0.05), no difference was observedin measles annual occurrences among the years under review and genders (p>0.05).Conclusion: This study recorded high incidence and case fatality of measles, which poses serious public health threat. Poordemographic data collection and storage were revealed thus, computerization of medical records for collection, storage andretrieval of data is imperative for adequate planning and control of measles imperil in Nigeria. J Microbiol Infect Dis 2016;6(1):12-18
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