Fusarium: A rare factor in diabetic foot infection
Diabetic foot infections are an important cause of morbidity. In humans, Fusarium causes external infections. A male obese patient at the age of 56 who had been getting treatment in various clinics due to ulceration and lymphedema. Treatment started with tigecycline 50 mg vial 2x1. Alcaligenes faecalis and Proteus vulgaris reproduced. Tigecycline treatment was stopped on the 4th day and piperacillin/tazobactam 4,5 gr vial 3x1 and liposomal amphotericin B 3 mg/kg/day were initiated. In direct microscopic examination, hypes were seen and Fusarium spp. reproduction was detected. Liposomal amphotericin treatment was stopped on the 15th day and voriconazole 200 mg tb po 2x1 was initiated. At the end of one month, the lesions were regressed entirely. It should not be forgotten that despite its scarcity, fungus factors might give rise to diabetic foot infections and patients should be evaluated in terms of fungus infections. J Microbiol Infect Dis 2017; 7(1): 42-45
Keywords:
Fusarium, Diabetic foot Voriconazole,
___
- 1. Lipsky BA, Berendt AR, Deery HG et al. Diagnosis and treatment of diabetic foot infections. Clin Infect Dis 2004; 39(7):895-910.
- 2. Lipsky BA, Berendt AR, Cornia PB et al. 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. Clin Infect Dis 2012; 54(12):e132-73.
- 3. Satman I, Omer B, Tutuncu Y et al. TURDEP-II Study Group, Eur J Epidemiol 2013; 28(2):169- 180.
- 4. American Diabetes Association. Consensus Development Conference on Diabetic Foot Wound Care: 7-8 April 1999, Boston, Massachusetts. J Am Podiatr Med Assoc. 1999;89(9):475-83.
- 5. Ozyurt M, Ardıc N, Turan K et al. The isolation of Fusarium sporotrichioides from a diabetic foot wound sample and identification. Marmara Medical Journal 2008; 21(1):68-72.
- 6. Bigley VH, Duarte RF, Gosling RD, Kibbler CC, Seaton S, Potter M. Fusarium dimerum infection in a stem cell transplant recipient treated successfully with voriconazole. Bone Marrow Transplant. 2004; 34(9):815-7.
- 7. Moschovi M, Trimis G, Anastasopoulos J, Kanariou M, Raftopoulou A, Tzortzatou-Stathopoulou F. Subacute vertebral osteomyelitis in a child with diabetes mellitus associated with Fusarium. Pediatr Int. 2004; 46(6):740-2.
- 8. Hemashettar BM, Siddaramappa B, Padhye AA, Sigler L, Chandler FW. White grain mycetoma caused by a Cylindrocarpon sp. in India. J Clin Microbiol 2000; 38(11):4288-91
- 9. Cocuroccia B, Gaido J, Gubinelle E, Annessi G, Girolomoni G. Localized cutaneous hyalohyphomycosis caused by a Fusarium species infection in a renal transplant patient. J Clin Microbiol. 2003;41(2):905-7.
- 10. Lipsky BA. New developments in diagnosing and treating diabetic foot infections. Diabetes Metab Res Rev 2008; 24 Suppl 1:S66-71.
- ISSN: 2146-3158
- Başlangıç: 2011
- Yayıncı: Sağlık Araştırmaları Derneği