Ticari Olarak Satın Alınan Nar Suyunun Antibakteriyal ve Bazı Antibiyotiklerle Sinerjistik Etkisi

Nar suyu günlük hayatamızda tükettiğimiz bir meyve suyu olup, narın sağlık açısından oldukça faydalı

Antibacterial Effect of Purchased Pomegranate Juice and Its Sinergistic Effect With Some Antibiotics

Pomegranate juice is a fruit juice that we consume in our daily life, and it is known that the pomegranateis very useful for health. In this study, it was aimed to determine the antibacterial activity of pomegranate juicewhich is commercially purchased and consumed against different Gr (+) and Gr (-) bacteria and its potentialsynergistic effect when it is used together with antibiotics. For this purpose, pomegranate juice branded “meySu”,which was purchased commercially, was used. According to results, Ampicillin, Gentamicin and pomegranatejuice exhibited different antibacterial effects against test bacteria (7.64-9.23, 22.26-22.98 and 19.07-20.14 mm,respectively). It was observed that pomegranate juice had the higher antibacterial effect than Ampicillin. Whenpomegranate juice and Ampicillin were applied together, it was seen that they formed the zone diameter between20.11-21.14 mm. When ponegranate juice and Gentamicin were applied together, they exhibited the inhibitionzones between 26.36-28.94 mm. These results showed that pomegranate juice exhibited the synergistic effect withboth of the standard antibiotics. The results of this study demostrated that pomegranate juice exhibited the highantibacterial activity against test bacteria used in this study. In addition, it is also important that pomegranate juiceshowed a synergistic effect when used with antibiotics tested in this study.

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  • Aviram M, Rosenblat M, 2012. Pomegranate protection against cardiovascular diseases. Evidence-Based Complementary and Alternative Medicine, doi:10.1155/2012/382763.
  • Aviram M, Volkova N, Coleman R, Dreher M, Reddy MK., Ferreira D, Rosenblat M, 2008. Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein E-deficient (E-o) mice and in vitro in cultured macrophages and upoproteins. Journal of Agricultural and Food Chemistry, 56: 1148–1157.
  • Collins CH, Lyne PM, Grange JM, 1989. Microbiological Methods. London, 410s.
  • Dağcı EK, Dığrak M, 2005. Bazı Meyve Ekstraktlarının antibakteriyal ve antifungal aktiviteleri. KSÜ Fen ve Mühendislik Dergisi, 8(2): 1-7.
  • Elmanama AA, Alyazji AA, Abu NA, 2011. Antibacterial, antifungal and synergistic effect of Lawsonia inermis, Punica granatum and Hibiscus sabdariffa. Annals of Alquds Medicine, 7: 33-41.
  • Glazer I, Masaphy S, Marciano P, Bar-Ilan I, Holland D, Kerem Z, Amir R, 2012. Partial identification of bioactive compounds having antifungal activities from Punica granatum peel extracts. Journal of Agricultural and Food Chemistry, 60(19): 4841–4848.
  • Hama AA, Taha Y, Qadir SA, 2014. The antimicrobial activity of pomegranate (Punica granatum) juice. International Journal of Scientific & Engineering Research, 5(10): 796-798.
  • Jayaprakasha G, Jena B, Negi P, 2006. Antimicrobial activities of pomegranate. Seeram NP, Schulman RN, Heber D (Ed.). Pomegranates: Ancient Roots to Modern Medicine. CRC Press, 167–183 p.
  • Langley P, 2000. Why a pomegranate. British Medical Journal, 321: 1153–1154.
  • Neurath AR, Strick N, Li YY, Debnath AK, 2005. Punica granatum (pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide. Annals of The New York Academy of Sciences, 1056: 311–327.
  • Orak HH, Demirci AŞ, Gümüş T, 2011. Antibacterial and antifungal activity of pomegranate (Punica granatum L. CV.) peel. Electronic Journal of Environmental Agricultural and Food Chemistry, 10(3): 1958-1969.
  • Özçelik S, 1992. Gıda Mikrobiyolojisi Laboratuar Kılavuzu. F.Ü. Fen-Edebiyat Fakültesi Yayınları, Yayın No: 1, Elazığ, 135s.
  • Quideau S, Deffieux D, Douat-Casassus C, Pouysegu L, 2011. Plant polyphenols: chemical properties biological activities, and synthesis. Angewandte Chemie International Edition in English, 50: 586–621
  • Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D, 2005. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. The Journal of Nutritional Biochemistry, 16: 360–367.
  • Seeram NP, Zhang Y, Reed JD, Krueger CG, Vaya J, 2006. Pomegranate phytochemicals. Seeram NP, Schulman RN, Heber D (Ed.). Pomegranates Ancient Roots to Modern Medicine. CRC Press, 3–29 p.
  • Zarei M, Azizi M, Zeinolabedin BS, 2011. Evaluation of Physicochemical Characteristics of Pomegranate (Punica granatum L.) Fruit during Ripening. Fruits, 66: 121-129.
Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi-Cover
  • ISSN: 2146-0574
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2011
  • Yayıncı: -