Barbitürik Asitin Enaminon Türevlerinin Sentezi ve Karakterizasyonu

Bu çalışmada barbitürik asitten türeyen dört enaminon türevi 5-formilbarbitürik asit ve seçilen birincil aminlerin reaksiyonu ile yüksek verimle sentezlenmiştir. Sentezlenen bütün bileşiklerinyapıları ATR-FTIR, 1H ve 13C NMR spektroskopileri kullanılarak kanıtlanmıştır. Bileşik 2d’nin yapısal karakterizasyonun da ayrıca 19F NMR spektroskopisi kullanılmıştır. Elde edilen spektroskopiksonuçlar literatürdeki rapor edilmiş benzer türevler ile uyumludur.

Anahtar Kelimeler:

Barbitürik asit, Enaminon, Kondenzasyon reaksiyonu, Spektroskopi

Synthesis and Characterization of Enaminone Derivatives of Barbituric Acid

In this study, four enaminones derived from barbituric acid were synthesized with the reaction of 5-formylbarbituric acid and selected primer amines with high yield. The structures of allcompounds were proved by using ATR-FTIR, 1H and 13C NMR spectroscopy. Also, 19F NMR spectroscopy was used for characterization of 2d. The obtained spectroscopic results have compliedwith reported similar derivatives in literature.

Keywords:

Barbituric acid, Enaminone, Condensation reaction, Spectroscopy,

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