Artemisia absinthium Bitki Ekstraktından Altın Nanopartiküllerin Çevre Dostu Hızlı Sentezi ve Antimikrobiyal Aktivitelerin Uygulanması

Nanopartiküller, üstün özelliklerinden dolayı birçok alanda kullanılmaktadır. Son zamanlarda, bu parçacıkların çevre dostu sentez yöntemleri kullanılarak üretilmesi çok popüler hale gelmiştir. Bu bağlamda, bu çalışmada, altın nanopartiküller (AuNP'ler), Artemisia absinthium'un (pelin otu) yeşil yaprak özütü ile hızlı ve çevre dostu bir yöntem kullanılarak sentezlenmiştir. AuNP'lerin tane boyutu Debye-Scherrer denklemine göre 13.40 nm olarak belirlendi. AuNP'lerin test edilen mikroorganizmaların büyümesi üzerindeki inhibe edici etkileri, minimum inhibe edici konsantrasyon (MİC) yöntemi ile belirlenmiştir. MİC, bir mikroorganizmanın büyümesini engelleyen bir antimikrobiyal maddenin minimum konsantrasyonu olarak tanımlanmaktadır. Elde edilen AuNP'ler, sırasıyla 0.250, 0.125, 0.125, 0.033 ve 0.66 mg mL-1 konsantrasyonlarında S. aureus, S. pyogenes, E. coli, P. aeruginosa suşları ve C. albicans mayası üzerinde önleyici etkiler göstermiştir.

Environmentally Friendly Rapid Synthesis of Gold Nanoparticles from Artemisia absinthium Plant Extract and Application of Antimicrobial Activities

Nanoparticles are used in many areas due to their superior properties. Recently, producing these particles using environmentally friendly synthesis methods has become very popular. Within this context, in this study, gold nanoparticles (AuNPs) were synthesized by using a quick, eco-friendly method with the green leaf extract of Artemisia absinthium (wormwood). The grain size of the AuNPs was determined as 13.40 nm according to the Debye-Scherrer equation. The inhibitory effects of the AuNPs on the growth of the tested microorganisms were determined by the minimum inhibitory concentration (MIC) method. The MIC is described as the minimum concentration of an antimicrobial agent that inhibits the growth of a microorganism. The obtained AuNPs were showed inhibitory effects on S. aureus, S. pyogenes, E. coli, P. aeruginosa strains and C. albicans yeast at concentrations of 0.250, 0.125, 0.125, 0.033 and 0.66 mg mL-1 respectively.

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Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi-Cover
  • ISSN: 2146-0574
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2011
  • Yayıncı: -
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