ÜROTELYAL MESANE KANSERİ NEDENİYLE RADİKAL SİSTEKTOMİ YAPILAN HASTALARDA PREOPERATİF HİDRONEFROZ İLERİ EVRE HASTALIĞI ÖNGÖREBİLİR
Amaç: Ürotelyal mesane kanseri nedeniyle radikal sistektomi yapılan hastalarda preoperatif olarak tespit edilen hidronefrozun onkolojik sonuçlara etkisini değerlendirmek Gereç ve Yöntem: Ocak 2006- Kasım 2016 tarihleri arasında ürotelyal mesane kanseri nedeniyle radikal sistektomi operasyonu yapılan 162 hasta çalışmaya dahil edildi. Hastalar preoperatif hidronefrozu olan (Grup 1) ve olmayan (Grup 2) olarak iki gruba ayrıldı. Bu iki grup hasta preoperatif ve postoperatif patolojik veriler açısından karşılaştırıldı. Bulgular: Preoperatif T evresi ve tümör grade’i açısından iki grup arasında anlamlı fark izlenmedi (p=0.177 ve p=0.909). Radikal sistektomi patolojisinde T evresi ve pozitif cerrahi sınır varlığı Grup 1’de anlamlı olarak daha yüksekti (p=0.014 ve p=0.002). Upstaging Grup 1 de anlamlı olarak daha yüksek bulundu (p=0.001). Sonuç: Ürotelyal mesane kanseri nedeniyle radikal sistektomi yapılan hastalarda preoperatif hidronefroz, ileri evre hastalığın göstergesi olabilir.
PREOPERATIVE HYDRONEPHROSIS CAN PREDICT ADVANCED DISEASE IN PATIENTS UNDERGOING RADICAL CYSTECTOMY DUE TO UROTHELIAL BLADDER CANCER
Introduction: To evaluate the effect of preoperative hydronephrosis on oncologic outcomes in patients undergoing radical cystectomy due to urothelial bladder cancer Material and Method: Between January 2006 and November 2016, 162 patients who underwent radical cystectomy due to urothelial bladder cancer were included in the study. Patients were divided into two groups as with (Group 1) and without (Group 2) preoperative hydronephrosis. Two groups were compared in terms of preoperative and postoperative pathological findings. Results: There were no significant difference between the groups in terms of preoperative T stage and tumor grade (p=0.177ve p=0.909). T stage and positive surgical margin presence in radical cystectomy pathology was significantly higher in Group 1 (p=0.014 ve p=0.002). Upstaging was significantly higher in group 1 (p = 0.001). Conclusion: Preoperative hydronephrosis can indicate advanced disease in patients undergoing radical cystectomy due to urothelial bladder cancer.
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