0.05). Preeklampsi ülkemizde obstetrik morbidite ve mortalitenin başlıca nedenlerindendir. Erken tanı koyup girişimde bulunmak hayati önem taşımaktadır. Preeklampsi tanısında 24 saatlik idrardaki protein miktarını ölçmek altın standarttır. Unutulmamalıdır ki preeklampsi ve eklampsi görülen hastaların küçük bir kısmında proteinüri görülmemektedir. Biz çalışmamızın verilerine dayanarak 24 saatlik idrardaki kalsiyum miktarının preeklampsi tanısında faydalı bir parametre olacağına inanmaktayız. OBJECTIVE:The aim of this study was to examine the relation between serum uric acid level, 24 hours urine protein, calcium,creatinine, uric acid levels and cretinine claearance in preeclamptic and normotensive pregnant women. STUDY DESIGN:The present study was conducted with 46 preeclamptic and 35 normotensive patients in 2000-2001. Serum uric acid and creatinine levels of all patients were determined. After collection of 24 hour urine, calcium, uric acid, creatinine, protein levels were determined and creatinine clearance calculated. All results were analysed by "Student's t test". RESULTS: Preeclamptic grup (group P) and control group (Group C) were adjusted for maternal age, getational age, BMI and gravida. The results in group P were as follows: Serum uric acid level 6.7+1.5 mg / dl, 24 hour proteinuria 4.126 + 2.5 gr., urine calcium 94.21 + 60.88 mg / 24 hours, urine creatinine 1130.71 + 333.1 mg / 24h and creatinine clearance 113.5 + 36.6 whilst they were respectively 4.01 ± 1mg / dl, 0.189 ± 0.1gr / 24h, 272.44 ± 122.1, 1110.99 ± 231.7mg / 24h and 58.18 ± 32.8 in the control group. Serum uric acid and 24 hour urine protein, were significantly higher in group P compared to Group C (p<0.05). In 24 hour urine, calcium and creatinine clearance were quite lower in Group P than Group C (p<0.05). In urine creatinine levels, no statisitically significant difference was found between two groups (p > 0.05). CONCLUSION: In the diagnosis of preeclampsia, measurement of protein in 24 hour urine is gold standard. It should be born in mind that proteinuria is not present only in a minority of patients with preeclampia and eclampsia. Bases on our findings, it is our contention that low calcium levels in 24 hour urine may be a useful parameter in the diagnosis of preeclampsia.">
[PDF] Preeclampsia and calciuria | [PDF] Preeklampsi ve kalsiüri
0.05). Preeklampsi ülkemizde obstetrik morbidite ve mortalitenin başlıca nedenlerindendir. Erken tanı koyup girişimde bulunmak hayati önem taşımaktadır. Preeklampsi tanısında 24 saatlik idrardaki protein miktarını ölçmek altın standarttır. Unutulmamalıdır ki preeklampsi ve eklampsi görülen hastaların küçük bir kısmında proteinüri görülmemektedir. Biz çalışmamızın verilerine dayanarak 24 saatlik idrardaki kalsiyum miktarının preeklampsi tanısında faydalı bir parametre olacağına inanmaktayız.">
0.05). Preeklampsi ülkemizde obstetrik morbidite ve mortalitenin başlıca nedenlerindendir. Erken tanı koyup girişimde bulunmak hayati önem taşımaktadır. Preeklampsi tanısında 24 saatlik idrardaki protein miktarını ölçmek altın standarttır. Unutulmamalıdır ki preeklampsi ve eklampsi görülen hastaların küçük bir kısmında proteinüri görülmemektedir. Biz çalışmamızın verilerine dayanarak 24 saatlik idrardaki kalsiyum miktarının preeklampsi tanısında faydalı bir parametre olacağına inanmaktayız. OBJECTIVE:The aim of this study was to examine the relation between serum uric acid level, 24 hours urine protein, calcium,creatinine, uric acid levels and cretinine claearance in preeclamptic and normotensive pregnant women. STUDY DESIGN:The present study was conducted with 46 preeclamptic and 35 normotensive patients in 2000-2001. Serum uric acid and creatinine levels of all patients were determined. After collection of 24 hour urine, calcium, uric acid, creatinine, protein levels were determined and creatinine clearance calculated. All results were analysed by "Student's t test". RESULTS: Preeclamptic grup (group P) and control group (Group C) were adjusted for maternal age, getational age, BMI and gravida. The results in group P were as follows: Serum uric acid level 6.7+1.5 mg / dl, 24 hour proteinuria 4.126 + 2.5 gr., urine calcium 94.21 + 60.88 mg / 24 hours, urine creatinine 1130.71 + 333.1 mg / 24h and creatinine clearance 113.5 + 36.6 whilst they were respectively 4.01 ± 1mg / dl, 0.189 ± 0.1gr / 24h, 272.44 ± 122.1, 1110.99 ± 231.7mg / 24h and 58.18 ± 32.8 in the control group. Serum uric acid and 24 hour urine protein, were significantly higher in group P compared to Group C (p<0.05). In 24 hour urine, calcium and creatinine clearance were quite lower in Group P than Group C (p<0.05). In urine creatinine levels, no statisitically significant difference was found between two groups (p > 0.05). CONCLUSION: In the diagnosis of preeclampsia, measurement of protein in 24 hour urine is gold standard. It should be born in mind that proteinuria is not present only in a minority of patients with preeclampia and eclampsia. Bases on our findings, it is our contention that low calcium levels in 24 hour urine may be a useful parameter in the diagnosis of preeclampsia.">
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