From backpain to paraplegia: A rare primary presentation of metastatic ovarian cancer in pregnancy

Epitelyal over kanserlerinin vertebraya metastazı oldukça nadir görülen ve genellikle otopsi sırasında saptanabilen bir komplikasyondur. Bu yazıda, ilk olarak parapleji ile başvuran ve torakal vertebra ve patolojik vertebra kırığına neden olan over kanseri saptanan nadir bir gebe olgu sunulmuştur.

Sırt ağrısından paraplejiye: Gebelikte saptanan nadir bir metastatik over kanseri olgusu

Vertebral metastasis from epithelial ovarian carcinoma is extremely rare and usually diagnosed at autopsy. We present here an unusual case of pregnant woman who developed paraplegy, due to thoracal vertebral metastasis and pathologic vertebral fracture of ovarian carcinoma.

Kaynakça

1. Perrin RG, Laxton AW. Metastatic spine disease: epidemiology, pathophysiology, and evaluation of patients. Neurosurg Clin N Am 2004;15(4):365-373.

2. Goodkin R, Carr BI, Perrin RG. Herniated lumbar disc disease in patients with malignancy. J Clin Oncol. 1987;5(4):667-671.

3. Elit L, Bocking A, Kenyon C, Natale R. An endodermal sinus tumor diagnosed in pregnancy: case report and review of the literature. Gynecol Oncol 1999;72(1):123- 127.

4. Cormio G, Rossi C, Cazzolla A, Resta L, Loverro G, Greco P, Selvaggi L. Distant metastases in ovarian carcinoma. Int J Gynecol Cancer 2003;13(2):125-129.

5. Abdul-Karim FW, Kida M, Wentz WB, Carter JR, Sorensen K, Macfee M, Zika J, Makley JT. Bone metastasis from gynecologic carcinomas: a clinicopathologic study. Gynecol Oncol 1990;39(2):108-114.

6. Park CM, Kim SH, Kim SH, Moon MH, Kim KW, Choi HJ. Recurrent ovarian malignancy: patterns and spectrum of imaging findings. Abdom Imaging 2003;28(3):404- 415.

7. Zhao XY, Huang HF, Lian LJ, Lang JH. Ovarian cancer in pregnancy: a clinicopathologic analysis of 22 cases and review of the literature. Int J Gynecol Cancer 2006;16 (1): 8-15.

8. Behtash N, Karimi Zarchi M, Modares Gilani M, Ghaemmaghami F, Mousavi A, Ghotbizadeh F. Ovarian carcinoma associated with pregnancy: a clinicopathologic analysis of 23 cases and review of the literature. BMC Pregnancy Childbirth 2008;8:1-7.

9. Schick U, Marquardt G, Lorenz R. Intradural and extradural spinal metastases Neurosurg Rev 2001;24(1):1-5.

10. Rose PG, Piver MS, Tsukada Y, Lau TS. Metastatic patterns in histologic variants of ovarian cancer. An autopsy study. Cancer 1989;64:1508-1513.

11. Pavlakis G, Mountzios G, Terpos E, Leivaditou A, Papadopoulos G, Papasavas P. Recurrent ovarian cancer metastatic to the sternum, costae, and thoracic wall after prolonged treatment with platinum-based chemotherapy: a case report and review of the literature. Int J Gynecol Cancer 2006;16 (l):299-303.

12. Wuntkal R, Maheshwari A, Gupta S, Tongaonkar H. Paraparesis: a rare primary presentation of epithelial ovarian cancer. Int J Gynecol Cancer 2006;16(1):293-294.

13. Bilsky MH, Lis E, Raizer J, Lee H, Boland P. The diagnosis and treatment of metastatic spinal tumor. Oncologist 1999;4:459-469.

14. Giuntoli RL 2nd, Vang RS, Bristow RE. Evaluation and management of adnexal masses during pregnancy. Clin Obstet Gynecol 2006;49:492-505.

15. Runge VM. Safety of approved MR contrast media for intravenous injection. J Magn Reson Imaging 2000;12(2): 205-213.

16. Marshall LF, Langfitt TW. Combined therapy for metastatic extradural tumors of the spine. Cancer 1977;40(5): 2067-2070.

17. Patchell RA, Tibbs PA, Regine WF, Payne R, Saris S, Kryscio RJ, Mohiuddin M, Young B. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet 2005;366 (9486): 643-648.

18. King LA, Nevin PC, Williams PP, Carson LF. Treatment of advanced epithelial ovarian carcinoma in pregnancy with cisplatin-based chemotherapy. Gynecol Oncol 1991;41(1): 78-80.

19. Rades D, Schild SE, Dunst J. Radiotherapy is effective for metastatic spinal cord compression in patients with epithelial ovarian cancer. Int J Gynecol Cancer 2007;17 (1): 263-265.

20. Altaras M, Rosen D, Shapira J, Cohen I, Bernheim J, Ravid M. Advanced primary ovarian carcinoma in pregnancy. Am J Obstet Gynecol 1989;160 (5): 1210-1211.

21. Creasman WT, Rutledge F, Smith JP. Carcinoma of the ovary associated with pregnancy. Obstet Gynecol 1971; 38 (1):111-116.

22. Machado F, Vegas C, Leon J, Perez A, Sanchez R, Parrilla JJ, Abad L. Ovarian cancer during pregnancy: analysis of 15 cases. Gynecol Oncol 2007;105 (2): 446-450.

23. Partridge EE, Phillips JL, Menck HR. The National Cancer Data Base report on ovarian cancer treatment in United States hospitals. Cancer 1996;78(10):2236-2246.

Kaynak Göster

  • ISSN: 1300-4751
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1995

3.8b 2.4b

Sayıdaki Diğer Makaleler

Evaluation of perinatal and maternal complications type of deliveries and neonatal outcomes in macrosomic and normal weighed newborns in our clinic between 2000 and 2010 years

Nurettin AKA, Sema SAYHARMAN ETİZ, Yasemin YAŞLAK, Gültekin KÖSE, Can TÜFEKÇİ

Primary pelvic involvement of hydatid disease

Miğraci TOSUN, Yıldırım DURAK, Handan ÇELİK, Devran BILDIRCIN, Mehmet Bilge ÇETİNKAYA, Ali Faik YILMAZ

From backpain to paraplegia: A rare primary presentation of metastatic ovarian cancer in pregnancy

Filiz ÇAYAN, Arzu DORUK, Aslı KÖSEOĞLU, Mutlu ALIMLI, Leyla CİNEL, Saffet DİLEK

Uterine lipoleiomyoma: Review of literature and two case reports

Nilüfer KANDEMİR ONAK, Figen BARUT, SİBEL BEKTAŞ, Burak BAHADIR, Banu GÜN DOĞAN, Neslihan KÖKTEN, Havva GÖKÇE, Aykut BARUT, Şükrü Oğuz ÖZDAMAR

Primary pelvic cyst hydatic

Sema SAYHARMAN ETİZ, Nurettin AKA, Gültekin KÖSE, Can TÜFEKÇİ, Kenan KARACA

Breus’ mole associated with hereditary thrombophilia in a teenage girl

Suna ÖZDEMİR, Osman BALCI, Ali Haydar KANTARCI, Tuba KOYUNCU, Cavide SÖNMEZ

Glucose challenge test and association with pregnancy outcome

ENİS ÖZKAYA, Burak KARADAĞ, Neslihan YEREBASMAZ, Oya ALDEMİR, Soner DÜZGÜNER, Evrim ÇAKIR, Salim ERKAYA

Adnexial mass in the adolescents

Evrim ERDEMOĞLU, İLKER GÜNYELİ, Mansur KAMACI, Tamer MUNGAN

Predictors of total gonadotropin dose required for follicular growth in controlled ovarian stimulation with intrauterin insemination cycles in patients with unexplained infertility or male subfertility

Berna DİLBAZ, ENİS ÖZKAYA, MEHMET ÇINAR, Evrim ÇAKIR, Serdar DİLBAZ

Galectin-3 expression in human endometrium and decidua during the menstrual cycle and in gestation

Nevra DURSUN, Melin GEÇER ÖZGÜN, Pelin YILDIZ, Cem LEBLEBİCİ, Erol Rüştü BOZKURT, Nimet KARADAYI, Fadime BAHADIR