Assessment of changes in uterine and subendometrial blood flows by doopler sonography in women undergoing assisted reproduction

AMAÇ: Bu çalışmanın amacı ICSI sikluslarında uterin Dopler kan akımı ve endometrial ve subendometrial kan akımlarının uterin reseptivite ile ilgisini araştırmaktır. GEREÇ VE YÖNTEM: Bu prospektif çalışma IVF-ET uygula nan 68 hasta üzerinde yapılmıştır.Hastaların hepsinde 3. Gün transfer edilen en az bir adet iyi kalite embryoları vardı. Renkli Doppler ultrasonografi incelemeleri Hcg günü ve midluteal dö nemde yapıldı.Uterin arter pulsatilite ve rezistans indexleri ve endometrial ve subendometrial kan akımları değerlendirildi. BULGULAR: Gebe kalan (n=16) ve gebe kalamayan (n=44) hastaların yaş,infertilite süreleri ve tranfer edilen embryo sayı ları istatistiksel olarak birbirine benzerdi.Her iki grubun ortala ma endometrial kalınlıkları hcg günü ve transfer sonrası 5-6 günü istatistiksel olarak birbirinden farklı değildi.Uterin arter re zistans index (RI) ve pulsatilite index (PI) ortalamaları hcg gü nü her iki grupta istatistiksel olarak farklı değilken,midluteal fazda her iki index gebe olan grupta gebe olmayanlara göre istatistiksel olarak anlamlı düşük olarak bulunmuştur.(p=0,05 ve p=0.016).Subendometrial kan akımı açısından iki grup ara sında anlamlı fark bulunmamıştır. SONUÇ: IVF-ET uygulanan hastalarda,hcg günü uterin arter doppler kan akımı ve subendometrial kan akımlarının ölçümü gebelik sonuçlarını etkilememektedir.Ancak midluteal düşük uterin arter PI değeri gebeliği predikte edebilir. Anahtar Kelimeler: Endometrial ve subendometrial kan akım ları, Doppler ultrasonografi, Uterin arter kan akımı, Asiste üre me teknikleri.

IVF-ET uygulanan kadınlarda doppler ultrasonografi ile uterin arter ve subendometrial kan akımlarının değerlendirilmesi

Objective: The aim of this study was to evaluate the relationship between uterine Doppler flow and endometrial and subendometrial blood flows and uterine receptivity during ICSI cycles. Study Design: A prospective observational study was conducted in sixty-eight women undergoing in-vitro fertilization-embryo transfer (IVF-ET) treatment. All of them had at least one good-quality embryo for transfer on the third day after oocyte retrieval. A color Doppler ultrasound examination was performed on the day of hCG injection and midluteal phase. Pulsatility and resistance index of uterine vessels, and vascularization and endometrial and subendometrial flows were evaluated. Results: The age, duration of infertility or number of embryos transferred of the women who conceived (n=16) and those who did not (n=44) did not statistically significantly differ. The mean endometrial thicknesses of the two groups on hCG day and 5-6days after embryo transfer were not statistically significantly different. The mean uterine arterial resistance index (RI) and Pulsatility Index (PI) values of the two groups were not significantly different on hCG day, but both indices were significantly lower in the pregnant than in the non-pregnant group in mudluteal phase (p=0.05 and 0.016, respectively). In addition, no significant differences were found between the two groups in subendometrial blood flow. Conclusion: In patients undergoing IVF-ICSI and embryo transfer, Doppler ultrasound examination of the uterine artery and subendometrial blood flow on hCG day do not discriminate the cycles resulting in conception and non-conception, but especially low mean PI of uterine artery in 5-6 days after ET can predict pregnancy.

Kaynakça

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Kaynak Göster

  • ISSN: 1300-4751
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1995

8.1b 3.4b

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