Yüksek irtifa antrenmanının pentatlon sporcularında oksidatif stres ve antioksidan savunma belirteçleri üzerine etkisi

Amaç: Çalışmanın amacı elit pentatlon sporcularında yükselti antrenmanın oksidatif stres ve antioksidan savunma sistemi belirteçleri üzerine etkilerini incelemekti. Gereç ve Yöntem: Çalışmaya 24-40 yaşları arasında, düzenli antrenman yapan on iki elit erkek pentatlon sporcusu katıldı. Sporcuların deniz seviyesindeki son antrenmanlarından 24 saat sonra istirahat kanları alındı. Daha sonra sporculara 2500 metre yükseklikte 4 hafta süreyle yükselti antrenmanı yaptırıldı ve antrenman sonrasında son antrenmandan 24 saat sonra sporculardan tekrar açlık kan örnekleri alındı. Kan örneklerinde malondialdehit (MDA), glutatyon (GSH) seviyeleri ve süperoksit dismutaz (SOD) aktivitesi analiz edildi. Bulgular: Sporcularda yüksek irtifa antrenmanından sonra antrenman öncesine göre MDA ve GSH seviyeleri artmıştı (P < 0,05), fakat SOD aktivitesinde herhangi bir değişiklik yoktu (P > 0,05). Sonuç: Bu çalışmadan elde ettiğimiz bulgulara göre yükselti antrenmanı elit pentatlon sporcularda oksidatif stresi artırıp enzimatik olmayan antioksidan sistemini güçlendirirken enzimatik antioksidan sistemini etkilemez.

Objective: The aim of this study was to investigate the effects of altitude training on oxidative stress and antioxidant system defense markers in elite pentathletes. Materials and Methods: Twelve elite male regularly trained pentathletes aged 24-40 years were participated in the study. Fasting blood samples were taken from the athletes 24 hours after the last training session at sea level. After that, athletes were performed altitude training at 2500 meters for 4 weeks and 24 hours after the last training session fasting blood samples were taken again. In the blood samples malondialdehyde (MDA), glutathione (GSH) levels and superoxide dismutase (SOD) activity were analyzed. Results: In the athletes, after the altitude training MDA and GSH were levels increased (P < 0.05), but SOD activity were not changed (P > 0.05) compared to the pre-training. Conclusion: According to the results obtained from this study, altitude training increased oxidative stress and improved non-enzymatic antioxidant system but does not affects enzymatic antioxidant system in the elite pentathletes.

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