Sennur DEMİREL, Ayşegül ZAMANİ, Tülin ÇORA, H. Gül DURAKBAŞI

Turner sendromu ve primer amenore olgularında serum çinko, bakır ve demir düzeyleri

Bu çalışma, Turner sendromlu ve primer amenoreli olguların serum çinko, bakır ve demir düzeylerini birbirleriyle ve sağlıklı kişilerle karşılaştırmak amacıyla yapıldı. Yöntem: Turner sendromlu, primer amenoreli hastalardan ve sağlıklı bireylerden oluşan kontrol grubundan alınan kan örnekleri santrifüj edilerek serumları ayrıldı ve -20 °C'de saklandı. Ölçümler atomik absorbsiyon/emisyon spektrofotometresi ile toplu olarak yapıldı. Bulgular: Turner sendromlu olgularda serum çinko düzeyinin primer amenoreli olgulardan ve kontrol grubundan düşük, serum bakır düzeyinin ise yüksek olduğu saptandı. Serum çinko ve bakır düzeyleri bakımından primer amenoreli grup ile kontrol grubu arasında fark bulunmadı. Her üç grubun demir düzeyleri arasında istatistiksel açıdan anlamlı bir fark saptanmadı. Sonuç: Turner sendromlu olgularda serum çinko düzeyinin düşük, serum bakır düzeyinin yüksek olduğu kanısına varıldı.

Serum zinc, copper and iron levels in patients with turner syndrome and primary amenorrhea

This study was performed in order to compare serum zinc, copper and iron levels between the patients suffering Turner syndrome and primary amenorrhea and also with healthy subjects. Methods: Peripheral blood samples were obtained from both group patients and healty subjects. Serum was separated by centrifugation and stored at -20 °C until the assay. Results: Patients with Turner syndrome had lower serum zinc and higher serum copper levels than the patients with primary amenorrhea and control groups. Serum zinc and copper levels were not different in primary amenorrhea and in control groups. In addition, there was not statistically significant difference between serum iron levels of all groups Conclusion: In patients with Turner syndrome serum zinc levels are lower and serum copper levels are higher than both primary amenorrhea and control groups.

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ISSN: 2602-3741
Yayın Aralığı: Yılda 6 Sayı
Başlangıç: 1997
Yayıncı: SELÇUK ÜNİVERSİTESİ > TIP FAKÜLTESİ

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