Kalsiyum pirofosfat dihidrat depolanma hastalığı (KPPD) olarak bilinen psödogut eklem aralığında kristal birikimi ile seyreden romatolojikbir hastalıktır. KPPD kristal depolanma hastalığı sıklıkla ileri yaşta aralıklı artrite neden olan bir hastalıktır. KPPD en sık olarak diz, el bileği, omuz ve kalça eklemlerini tutar. Hiperparatiroidizm, hemokromatozis, hipomagnezemi, hipofosfatemi KPPD ile ilişkilidir. İleri yaşta monoartritle başvuran hastalarda KPPD ayırıcı tanıda düşünülmelidir. Bu çalışmada KPPD ve paratiroid adenomu saptanan olgu sunulmaktadır.
Pseudogout, also known as calcium pyrophosphate dehydrate deposition disease(CPPD), is arheumatological condition arising from accumulation of calcium pyrophosphate dehydrate crystals in connective tissues.Calcium pyrophosphate dehydrate deposition disease (CPPD) is the disease caused intermittent arthritis. It predominatly affects the elderly. Target joints include the knees ,wrists,shoulders and hips. Hyperparathyroidism, hemocromatosis, hypomagnesemia, hypophosphatemia associate with CPPD. Acase of CPPD withparathyroid adenomais presented in this report.
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Felson DT, Anderson JJ, Naimark A, et al.The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham Study. J Rheumatol 1989;16:1241-5.
Musacchio E, Ramonda R, Perissinotto E, et al.The impact of knee and hipchondrocalcinosis on disability in older people: theProVA Study from north eastern Italy. Ann Rheu Dis 2011;70:1937-43.
Felson DT, Anderson JJ, Naimark A, et al.The prevalence of chondrocalcinosis in the elderly and its association with kneeosteoarthritis: theFraminghamStudy. J Rheumatol 1989; 16:1241-5.
Jones AC,Chuck AJ, Arie EA, et al.Diseases associated with calciumpyrophosphate deposition disease. Semin ArthritisRheum 1992;22:188-202.
Jones AC, Chuck AJ, Arie EA, et al. Diseasesassociated with calciumpyrophosphate deposition disease. Semin Arthritis Rheum 1992; 22:188.
Filippou G, Frediani B, Gallo A, et al.A "new" techniquefor the diagnosis of chondrocalcinosis of the knee: sensitivity and specificity of high-frequency ultrasonography. Ann Rheum Dis 2007;66:1126-8.
Richette P, AyoubG, Lahalle S, et al. Hypomagnesemia associated with chondrocalcinosis: a cross-sectional study. Arthritis Rheum 2007;57:1496-501.
Mc Carty DJ. Calcium pyrophosphate dihydrate crystal deposition disease-1975. Arthritis Rheum 1976; 19 Suppl3:275.
TEMD Osteoporoz ve Metobolik Kemik Hastalıkları Tanı ve Tedavi Kılavuzu 2017, s:145.
Zhang W, Doherty M, Pascual E, et al. EULAR recommendations for calcium pyrophosphate deposition. Part II: management. Ann Rheum Dis 2011; 70:571.