Kadir DURGUT, Niyazi GÖRMÜŞ, Ufuk ÖZERGİN

HIV-negatif Kaposi sarkomu

Amaç: Nadir görülen HIV- negatif Kaposi sarkomunun ve eşlik eden lezyonların tanımlanması amaçlanmıştır. Olgu sunumu: 65 yaşındaki bir erkek hastada Kaposi sarkomunun deri lezyonları ve lenfödem ortaya çıktı. Hastada sağ bacak, sol el bileği ve alında kahverengi-siyah renkli ağrısız papül şeklinde birbiriyle birleşik lezyonlar mevcuttu. Sonuç: Kaposi sarkomu nadir bir karsinom türüdür. Bu çalışmada Kaposi sarkomu ve literatür gözden geçirilmiştir.

Anahtar Kelimeler:

İmmün yetmezlik sendromları, Damar neoplazmları, Deri hastalıkları, Lenf ödem, Edinilmiş immün yetmezlik sendromu, Sarkom, Kaposi

HIV-negative Kaposi's sarcoma: A case report

Objective: It was aimed to report a rarely seen HIV- negative Kaposi’s sarcoma and associated lesions. Case report: A 65-year-old male patient developed skin lesions of Kaposi’s sarcoma and lymphoedema. The patient had large areas of confluent, violaceous or brown-black painless papules on the right leg and the left wrist and the forehead. Conclusion: Kaposi’s sarcoma is a rare form of carsinoma. In the present article, we summarize the Kaposi’s sarcoma and review the literature.

Keywords:

Immunologic Deficiency Syndromes, Vascular Neoplasms, Skin Diseases, Lymphedema, Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi,

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Pfister M, Vogt B. Painless, red- violet skin lesions during immunosupression. Ann Diagn Pathol 1997;1:57-64.
McGarvey ME, Tulpule A, Cai J, Zineng T, Masood R, Espina B, et al. Emerging treatments for epidemic (AIDS-related) Kaposi’s sarcoma. Int J STD AIDS 1998;9:518-25.
Cathomas G, Tamm M, McGandy CE, Perruchoud AP, Mihatsch MJ, Dalquen P. Detection of herpesvirus-like DNA in the bronchoalveolar lavage fluid of patients with pulmonary Kaposi’s sarcoma. Eur Respir J 1996;9:1743-6.
Lebbe C. Kaposi’s disease. Scan J Infect Dis 1998;30:613-5.
Gaspari AA, Marchese S, Powell D, Raddy PL, Tyring SK. Identification of HHV-8 DNA skin lesions of Kaposi’s sarcoma in an immunosuppresed patient with bullous pemphigoid. J Am Acad Dermatol 1997;37:843-7.
Lebbé C, Blum L, Pellet C, Blanchard G, Verola O, Morel P, et al. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi’s sarcoma. AIDS 1998;12:45-9.
Bobroski L, Bagasra AU, Patel D. Localization of human herpes virus type 8 in the Kaposi’s sarcoma tissues and the semen specimens of HIV-1 infected and uninfected individuals by utilizing in situ polymerase chain reaction. Rev Epidemiol Sante Publique 1999;47:109-17.
Renwick N, Halaby T, Weverling GJ, Dukers NH, Simpson GR, Coutinho RA, et al. Seroconversion for human herpesvirus 8 during HIV infection is highly predictive of Kaposi’s sarcoma. AIDS 1998;12:2481-8.
Hsiao CH, Su IJ, Hsieh SF, Huang SF, Tsai TF, Chen MY, et al. Epstein- Barr virus-associated intravascular lymphomatosis within Kaposi’s sarcoma in an AIDS patient. Am J Surg Pathol 1999;23:482-7.
Fonseca R, Witzig TE, Olson LJ, Edwards BS, Khoor A, Walker RJ. Disseminated Kaposi’s sarcoma after heart transplantation: Association with Kaposi’s sarcoma-associated herpes virus. J Heart Lung Transplant 1998;17:732-42.
Krengel S, Goerdt S, Krüger K, Schnitzler P, Geiss M, Tebbe B, et al. Kaposiform HHV-8 negative acroangiodermatitis in chronic. Hautarzt 1999;50:208-13.
Orenstein JM, Alkan S, Blauvelt A, Jeang KT, Weinstein MD, Ganem D, et al. Visualization of human herpesvirus type 8 in Kaposi’s sarcoma by light and transmission electron microscopy. AIDS 1997;11:F35-45.
Newell M, Milliken S, Goldstein D, Lewis C, Boyle M, Dolan G, et al. A phase II study of liposomal doxorubicin in the treatment of HIV-related Kaposi’s sarcoma. J Gen Virol 1999;80:549-55.
Coukell AJ, Spencer CM. Polyethylene glycol- liposomal doxorubicin: A review of its pharmocodynamic and pharmocokinetic properties, and therapeutic efficacy in the management of AIDS- related Kaposi’s sarcoma. Drugs 1997;53:520-38.
Ritz Quillac L, Machet L, Machet MC, Vedere V, Vaillant L, Lorette G. Bone involvement in a case of Kaposi’s sarcoma. Dermatology 1999;198:73-4.
Tur E, Brenner S. Classic Kaposi’s sarcoma: Low-dose interferon alfa treatment. Br J Haematol 1998;103:788-90.
Üskent N, Danacı M, Altınok Z, Cebeci BS, Özel M. AIDS ilişkisiz Kaposi sarkomunun alfa 2-2b interferona cevabı. Ankem Derg 1990;4:302.
Tavio M, Nasti G, Simonelli C, Vaccher E, De Paoli P, Giacca M, et al. Human chorionic gonadotropin in the treatment of HIV- related Kaposi’s sarcoma. Eur J Cancer 1998;34:1634-7.

ISSN: 2602-3741
Yayın Aralığı: Yılda 6 Sayı
Başlangıç: 1997
Yayıncı: SELÇUK ÜNİVERSİTESİ > TIP FAKÜLTESİ

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