Nesibe AKYÜREK, Mehmet Emre ATABEK, BERAY SELVER EKLİOĞLU, Sevil ARI YUCA

Hiperkalseminin eşlik ettiği cilt altı yağ nekrozu

Cilt altı yağ nekrozu nadir görülen; gövdede, kollarda, bacaklarda ve yanaklarda ağrılı, eritematöz plak ya da nodüller şeklinde ortaya çıkan yağ dokusunun inflamatuvar iyi huylu hastalığıdır. Cilt altı yağ nekrozu olan yenidoğanlarda sıklıkla asfiktik doğum, mekon- yum aspirasyonu, hipoksi, hipotermi, lokal travma öyküsü mevcuttur. Kendi kendini sınırlayan bir hastalık olmakla beraber ağır hiperkalsemi, hiperlipidemi, geçici trombositopeni gibi komplikasyonlara yol açabilir. Özellikle yaygın cilt tutulumu olan hastalarda hiperkalsemi hayatı tehdit eden bir komplikasyondur. Hiperkalsemiye maruziyet süresi uzarsa metastatik kalsifikasyonlar, nefrokal- sinosis ve böbrek yetmezliği, kalp problemleri ortaya çıkabilir. Bu yazıda bebeklik döneminde hiperkalsemin eşlik ettiği cilt altı yağ nekrozu vakası sunulmuştur.

Subcutaneous fat necrosis with hypercalcemia

Subcutaneous fat necrosis is a rare and bening inflammatory disease of adipose tissue. It manifests as painful erythematous plaques and nodules in trunk, extremities and cheeks. Neonates with subcutaneous fat necrosis, often had a history of asphyxia ,meconium aspiration, hypoxia, hypothermia and local trauma. Although it is a self-limiting disease, it can lead to complications such as severe hypercalcemia, hyperlipidemia, and transient thrombocytopenia. Especially in patients with extensive skin involvement, hypercalce- mia is a life threatening complication. If exposure to hypercalcemia takes a long time, metastatic calcification, nephrocalcinosis and renal failure, cardiac problems may occur. In this article, a case of subcutaneous fat necrosis accompanied by hypercalcemia in an infant was reported.

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