Demet KIREŞİ, Mehmet SEVGİLİ, Saim AÇIKGÖZOĞLU, Nazmi ZENGİN

Diabetik retinopatide oküler kan akımının renkli Doppler ultrasonografi değerlerinin karşılaştırılması

Amaç: Proliferatif ve nonproliferatif diabetik retinopatili hastalarda oftalmik arter (OA) ve santral retinal arterdeki (SRA) kan akımı değişikliklerini araştırmak, sonuçları sağlıklı kontrol grubunun bulguları ile karşılaştırmak ve Doppler ultrasonografi bulgularını değerlendirmek. Yöntem: Bu araştırmaya 39 diabetik retinopatili [23’ü nonproliferatif retinopati (NPRP), 16’sı proliferatif retinopati (PRP)] hasta ve aynı yaş grubundan 19 sağlıklı birey katıldı. Renkli Doppler ultrasonografi ile OA ve SRA’nın en yüksek sistolik akım hızı (Vp), ortalama akım hızı (Vm), diastol sonu akım hızı (Vd), rezistivite indeksi (RI) ve pulsatilite indeksi (PI) ölçüldü. NPRP, PRP ve kontrol gruplarının sonuçları istatistiksel olarak karşılaştırıldı. Bulgular: Sağ ve sol gözler arasında tüm gruplarda anlamlı farklılık saptanmadı. Oftalmik arterin; kontrol grubu ile NPRP ve PRP grupları arasında tüm değerlerde ve NPRP grubu ile PRP grubu arasında Vp ve Vm değerleri dışında tüm değerlerde anlamlı fark vardı. Santral retinal arterin; kontrol grubu ile NPRP grubu arasında ve kontrol grubu ile PRP grubu arasında Vp dışında tüm değerler arasında anlamlı fark mevcuttu. NPRP ile PRP grupları arasında ise PI ve RI değerlerinde anlamlı fark görüldü. Sonuç: Diabetik retinopatili hastalarda sağlıklı bireylere göre orbital vasküler yapılarda hemodinamik değişiklikler olmaktadır. Bu değişiklikler Doppler ultrasonografi ile ölçülebilir. Bu ölçümlerden Doppler açısına bağımlı olmayan RI ve PI’nin daha güvenli olduğu söylenebilir.

The correlation of colour Doppler ultrasound findings of orbital blood flow in diabetic retinopathy

Objective: To measure and investigate the changes of blood flow velocity of ophthalmic artery (OA), central retinal artery (CRA) in proliferative and nonproliferative diabetic retinopathy by colour Doppler imaging, to compare the results with those of the healthy controls, and to evaluate of Doppler ultrasound findings. Methods: In this study, we examined 39 patients with diabetic reitnopathy (23 patients with nonproliferative and 16 patients with proliferative) and 19 healthy subjects. We measured the peak systolic velocity (PSV), mean velocity (MV), end-diastolic velocity (EDV), resistance index (RI), and pulsatilty index (PI) of OA and CRA by color Doppler imaging. The results of each groups was compared with statistical analysis. Results: There was no significant difference in the indices of the right eyes compared to those of the left eyes. There was a statistically significant increase in the velocity of the ophthalmic artery in the healthy group compared with the groups NPRP and PRP. Also, a statistically significant difference in EDV, RI, and PI of OA was found in the NPRP group compared with PRP. There were significant differences in all of the measured values except PSV of CRA in the healthy group compared with NPRP and PRP groups. RI and PI values of CRA were found significantly higher in the group PRP than in the NPRP. Conclusion: The blood flow values of orbital vascular structures have some hemodynamic differences in DR patients compared with healthy individuals. These differences can be measured by Doppler US. The independent values of Doppler angle such as RI and PI may be more reliance.

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