Relationship between estradiol level and sleep quality in healthy women

Amaç: Uyku kalitesi üzerinde seks hormonlarının etkisi genellikle postmenopozal kadınlarda çalışılmıştır. Çalışmamızda, menapozda olmayan kadınlarda serum estradiol düzeyleri ile uyku kalitesi arasındaki ilişkiyi araştırmayı amaçladık. Gereç ve Yöntemler: Çalışmamıza psikiyatrik, jinekolojik yada sistemik hastalığı olmayan, 100 sağlıklı kadın dahil edilmiştir. Uyku kalitelerini değerlendirmek için Pittsburg Uyku Kailite İndeksi (PSQI) uygulanmıştır ve menstrüel peryodun 3.gününde serum estradiol düzeylerine bakılmıştır. Bulgular: Ortalama serum estradiol düzeyleri 208.12±82.028 pg/ml'dir. Ortalama PSQI skoru 5.40±4.357 ‘dir. Ortalama serum estradiol düzeyleri 'iyi uyuyanlar' olarak adlandırılan gurupta (PSQI skoru

Sağlıklı kadınlarda serum estradiol düzeyleri ile uyku kalitesi arasındaki ilişki

Objective: The effect of sex hormones on sleep quality was studied mostly in postmenopausal women. In our study we aimed to investigate the effects of estradiol level on sleep quality in premenopausal healthy women. Materials and Methods: One hundred healthy women without any psychiatric, gynecologic or systemic disease and assessed their sleep quality by Pittsburg Sleep Quality Index (PSQI) were enrolled to the study and their estradiol levels were obtained on the third day of their menstrueal cycles. Results: Mean serum estradiol level was 208.12±82.028. The mean of global PSQI scores was 5.40±4.357. The mean estradiol level in “good sleepers” (PSQI score < 5) was 243.80±76.07 while the mean estradiol level in “poor sleepers” (PSQI score≥5) was 154.60±58.55, thus estradiol level was significantly higher in “good sleepers” group (t= −6.276; p<0.001). Conclusion: We found that in normally cycling healthy women, estrogen level in normal range is also important in determining subjective sleep quality.

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