Yenidoğan Buzağı İshallerinin Önemli Viral Etkenlerinden Caliciviruslar
Sığır yetiştiriciliğinin önemli hastalıklarından biri olan yenidoğan buzağı ishalleri virus, bakteri, protozoon gibi birçok enfeksiyöz ajanın yanı sıra çevresel koşullar, bakım ve beslenme gibi etkenlerden de kaynaklanabilmektedir. Viral enfeksiyöz etkenlerin başında sıklıkla Bovine Rotavirus A, Cryptosporidium parvum, Bovine Coronavirus ve E. coli gibi etkenler tespit edilmektedir. Son yıllarda ise hem insanlarda hem de hayvanlarda önemli enfeksiyonlara neden olan Caliciviruslar yenidoğan buzağı ishallerinden sorumlu ajanlar olarak kabul edilmektedir. Caliciviruslardan Norovirus genogrup III ve Nebovirus “Bovine Enteric Caliciviruslar (BEC)” olarak tanımlanmaktadırlar. Bu etkenler günümüzde buzağı ishallerinin rutin teşhisinde yer almamasına karşın yapılan çalışmalar BEC’lerin tek başına ya da diğer enteropatojenler ile birlikte buzağı ishal olgularının gelişmesinde önemli rol oynadığını ortaya koymaktadır. Bu derleme ile Bovine Enteric Calicivirusların yapısal özellikleri ve bu virusların neden olduğu enfeksiyonlara ilişkin detaylı bilgilerin sunulması amaçlanmıştır.
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