Mehmet DEMİRCİ, Akın YİĞİN, Nadire ESER, Hikmet DİNÇ

Sularda, İnsan Enfeksiyonları ile İlişkili Norovirus Genogruplarının Real-Time PCR Yöntemi ile Saptanması

İnsan norovirüsü (HNoV), çevresel etkenlere oldukça dirençli bir RNA virüsüdür ve akut viral gastroenteritin nedeni olan ana etkenlerden birisidir. Hızlı evrim yeteneği nedeniyle 7 genogrubu vardır ve bunlardan GI, GII ve GIV insan enfeksiyonları ile ilişkilidir. Sular HNoV için salgın aracı olarak tanımlamaktadır. Bu bilgiler ışığında, çalışmamızda, lokal kuyular ve derelerden alınan su numunelerinde özellikle insanlarda enfeksiyonları ile ilişkili HNoV genogrup (G)I, GII ve GIV varlığının gerçek zamanlı polimeraz zincir reaksiyonu (real-time PCR) ile tanımlanarak moleküler epidemiyolojik bir veri sağlanması amaçlanmıştır.

Anahtar Kelimeler:

Su, real-time PCR, Norovirüs genogrupları

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