Kanatlı Hayvanlarda Mukozal Bağışıklık

Antijenler vücuda mukozal alanlardan girer. Enfeksiyonlar mukozalarda oluşur ve yayılır. Mukozal lenfoid dokular (MALT), spesifik ve nonspesifik bağışıklığı birlikte uyararak antijenleri giriş yerinde yok ederler ve antijenin yayılmasını engeller. Kanatlı hayvanlar sindirim (GALT), solunum (Harderian bez, CALT, NALT, BALT) ve genital sistemde bulunan mukozal lenfoid dokuları ile gelişmiş bir mukozal bağışıklık sistemine sahiptir. Ancak kanatlı hayvanların mukozal lenfoid dokularının özellikleri ve savunma mekanizmalarına dair sınırlı bilgi vardır. Bu derleme kanatlı hayvanlarda bulunan mukozal lenfoid dokuları birlikte sunarak enfeksiyonların önlenmesindeki rolüne ve yeni mukozal aşı stratejileri geliştirilmesine katkıda bulunacaktır.
Anahtar Kelimeler:

BALT, CALT, GALT, Kanatlı, NALT

Mucosal immunity in poultry

Antigens enter the body throught the mucosal surfaces. Infections occur and spread in mucosal surfaces. Mucosal lymphoid tissues (MALT), prevent specific and nonspecific immunity from spreading the antigens at the site of introduction by stimulating together. Poultry animals have a mucosal immune system developed with digestion (GALT), respiratory (Harderian gland, CALT, NALT, BALT) and mucosal lymphoid tissues found in the genital system. However, there are limited information about the properties and defense mechanisms of mucosal lymphoid tissues of poultry. This review will contribute to the role of prevention of infections and the development of novel mucosal vaccine strategies by presenting mucosal lymphoid tissues in poultry.

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Etlik Veteriner Mikrobiyoloji Dergisi-Cover
  • ISSN: 1016-3573
  • Yayın Aralığı: Yılda 2 Sayı
  • Başlangıç: 1960
  • Yayıncı: Veteriner Kontrol Merkez Araştırma Enstitüsü Müdürlüğü
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