Objective:To determine the incidence, clinical and histopathological presentations of the paranasal sinus tumors in Komfo AnokyeTeaching Hospital, Kumasi, Ghana.Methods:All cases of sinonasal cancers diagnosed between January2007 and December 2012 were retrospectively reviewed.Results: Of the 68 patients (38 males, 30 females) whose charts werereviewed, the median age was 49 (range: 14 to 84) years. The commonclinical presentations were epistaxis (23%), nasal mass (20%), headache(12%), nasal blockage (12%), nasal discharge (11%), proptosis (9%),cheek swelling (8%), and epiphora (5%). The most commonhistopathological subtypes were squamous cell carcinoma (39.6%) andadenocarcinoma (25%). Conclusion:Sinonasal tumors are frequent in male adults and present with epistaxis, nasal mass, blocked nose and nasal discharge, whilesquamous cell carcinoma remains the common histopathologicaltype
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1. Kuijpens JHLP, Louwman MWJ, Peters R, Janssens GORJ, Burdorf AL, Coebergh JWW. Trends in sinonasal cancer in The Netherlands: more squamous cell cancer, less adenocarcinoma. A population-based study 1973-2009. Eur J Cancer 2012;48: 2369–74.
2. Myers LL, Nussenbaum B, Bradford CR, Teknos TN, Esclamado RM, Wolf GT. Paranasal sinus malignances: an 18- year single institution experience. Laryngoscope 2002;112:1964– 9.
3. Dulguerov P, Jacobsen MS, Allal AS, Lehmann W, Calcaterra T. Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review. Cancer 2001;92: 3012–29.
4. Weber AL. Tumors of the paranasal sinuses. Otolaryngol Clin North Am 1988;21:439–54.
5. Settipane GA. Epidemiology of nasal polyps. Allergy Asthma Proc 1996;17:231–6.
6. Arnold A, Ziglinas P, Ochs K, et al. Therapy options and longterm results of sinonasal malignancies. Oral Oncol 2012;48: 1031–7.
7. Betlejewski S, Bilewicz R, Stankiewicz C, et al. Malignant tumours of the nose and paranasal sinuses in the years 1992–2001. [Article in Polish] Otolaryngol Pol 2006;60:729–36.
8. Fasunla AJ, Lasisi AO. Sinonasal malignancies: a 10-year review in a tertiary health institution. J Natl Med Assoc 2007;99:1407– 10.
9. Brobby GW. Cancer of the maxillary sinus and its management in Kumasi, Ghana. Journal of the University of Science and Technology (Kumasi) 1988;8:1–6.
10. Myers LL, Oxford LE. Differential diagnosis and treatment options in paranasal sinus cancers. Surg Oncol Clin North Am 2004;13:167–86.
11. Koivunen P, Mäkitie AA, Bäck L, et al. A national series of 244 sinonasal cancers in Finland in 1990–2004. Eur Arch Otorhinolaryngol 2012;269:615–21.
12. Waldron JN, O’Sullivan B, Gullane P, et al. Carcinoma of the maxillary antrum: a retrospective analysis of 110 cases. Radiother Oncol 2000;57:167–73.
13. Madison Michael L 2nd, Sorenson JM, Samant S, Robertson JH. The treatment of advanced sinonasal malignancies with preoperative intra-arterial cisplatin and concurrent radiation. J Neurooncol 2005;72:67–75.
14. Zyłka S, Bień S, Kamiński B, Postuła S, Ziołkowska M. Epidemiology and clinical characteristics of sinonasal malignancies. [Article in Polish] Otolaryngol Pol 2008;62:436–41.
15. Carrau RL, Myers EM, Johnson JT. Paranasal sinus carcinoma – diagnosis, treatment and prognosis. Oncology (Williston Park) 1992;6:43–50; discussion 55–6.