Tip 2 diabetes mellitus hastalarında serum transferin reseptör düzeyleri

Bu çalışmada tip 2 diabetes mellitus'lu ( DM ) 45 erişkin hasta ile 32 sağlıklı bireyin serum "soluble" transferin reseptör (STfR) düzeyleri araştırıldı. Diyabetik hasta grubunda demir eksikliği, kronik hastalık, böbrek yetmezliği olmak üzere anemi nedeni olabilecek bir patoloji yoktu. Serum STfR düzeyleri diyabetik hastalarda 1.237$pm$0.250 mg/L iken sağlıklı kontrollerde 1.217$pm$0.315 mg/L bulundu (p=0.760). Serum STfR düzeyleri, cinsiyet farkı göstermiyordu. Sonuçlar, serum STfR düzeyinin diabetik parametrelerden etkilenmediğini ve bu hastalarda demir eksikliğini göstermede duyarlı bir test olabileceğini göstermektedir.

Anahtar Kelimeler:

Anemi, demir eksikliği, Transferrin, Diabetes mellitus, insülin bağımsız, Reseptörler, albumin

Serum transferrin receptor levels in the patients of diabetes mellitus type 2

In this study, serum STfR levels of 45 diabetic patients and 32 healthy adults were measured. There was not any pathology causing anemia, such as iron deficiency, chronic disease and renal insufficiency. Serum STfR level was 1.237$pm$0.250 mg/L in the diabetic patients, and 1.217$pm$0.315 mg/L in the healthy group (p=0.760). There was no difference between males and females. The results suggested that the level of STfR was not affected by diabetic parameters, and that might be a sensitive test to diagnose iron deficiency in diabetic patients.

Keywords:

Anemia, Iron-Deficiency, Transferrin, Diabetes Mellitus, Non-Insulin-Dependent, Receptors, Albumin,

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