Three cases of paralysis secondary to hypokalemia and rhabdomyolysis caused by licorice root consumption
Meyan kökü, özellikle Türkiye'nin doğusunda sıcak mevsimlerde yaygın tüketilen bir içecektir. Bu içecek özellikle ramazan aylarında bol miktarda tüketilmektedir. Bu yazıda, aşırı meyan kökü tüketimi sınrası kas güçsüzlüğü, hipokalemi, rabdomyoliz ve hipertansiyon gelişen ve potasyum replasmanı ile klinikleri düzelen 3 olgu sunduk.
Meyan kökü tüketimi nin neden olduğu hipokalemi ve rabdomiyolize sekonder olarak gelişen üç paralizi olgu su
Licorice root is a widely consumed drink in warm seasons, especially in the East of Turkey. This drink is consumed plentifully especially in the month of Ram adan. We hereby presented 3 cases with muscle weakness, hypokalemia, rhabdomyolysis and hypertension developed secondary to excessive consumption of licorice root, which resolved with potassium replacement.
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1. Meltem AC, Coskun F, Nalan MA, et al. A hypokalemic muskular weakness licorice ingestion. Cases J 2009;2:8053.
2. Shibata S. A drug over the millennia: Pharmacognosy, chemistry and pharmacology of licorice. Yakugaku Zasshi 2000;120(10):849 -62.
3. Hamidon BB, Jeyabalan V. Exogenously-induced apparent hypermineralocorticoidism associated with ingestion of 'asam boi. Singapore Med J 2006; 47(2) : 156 -8.
4. Kusano E. How to diagnose and treat a licorice -induced syndrome with findings similar to that of primary hyperaldosteronism. Intern Med 2004; 43(1): 5 -6.
5. Nielsen H , Landbo K. Hypokalemia, myopathy with myoglobinuria after prolonged ingestion of licorice. Ugeskr Laeger 1970;132(38):1778 -80.
6. Kageyama Y, Suzuki H, Saruta T. Glycyrrhizin induce d mineralocorticoid activity through alterations in cortisol metabolism in the human kidney. J Endocrinol 1992; 135(1): 147 -52 .
7. Van den Bosch AE, van der Klooster JM, Zuidgeest DM, Ouwendijk RJ, Dees A. Severe hypokalaemic paralysis and rhabdomyolysis due to ingestion of licorice. Neth J Med 2005;63(4):146 -8.
8. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Mayo Clin Proc 2003; 78(6) :767 -8 .