Çalışmamızın amacı farklı volümde (tek set-çok set) ancak aynı şiddette [8-12Tekrar Maksimum(RM) ve 12-15 RM] yapılan sekiz haftalık direnç antrenmanlarının kemik turn-over markerleri üzerine etkisinin incelenmesi. Metod: 42 sağlıklı erkek üniversite öğrencisi rasgele tek set (TSG; n=14), çok set (ÇSG; n=13) ve kontrol grubu (KG; n=15) olarak ayrıldı. ÇSG tüm egzersizleri ilk üç hafta 3 set, 12-15RM ile; geri kalan 5 hafta ise süper set ve 3 set halinde 8-12RM ile, tüm çalışma boyunca haftada 3 gün olarak yaptı. TSG ise tüm egzersizleri tek set olarak yaptı. Çalışma döneminin başında ve sonunda serumda total alkalen fosfataz (ALP), kalsiyum (Ca +), fosfat, paratiroid hormonu (PTH), osteokalsin (OC), idrarda deoksipiridinolin (DPD) düzeyleri ölçüldü.PTH TSG, ÇSG ve KG'de sırasıyla %15.32 (p

The aim of the study was to investigate whether different training volume (single set vs. multiple sets) but equal intensity [8-12 Repeat Maximum (RM) and 12-15 RM] of 8-week weight training would lead to different changes in bone mineral metabolism.Method: 42 healthy male college students were randomly placed into single set group (SSG; n= 14), multiple-set group (MSG; n= 13) or control group (CG; n= 15). MSG performed all exercises in 3 sets of 12-15 RM for the first three weeks;süper sets and 3 sets of 8-12 RM were performed for the remaining 5 weeks; 3days/week. SSG performed all exercises 2+ m one set. Serum total alkaline phosphatase (ALP), calcium (Ca ) phosphate, parathyroid hormone (PTH), osteocalcin (OC), and'urinary deoxypyridinoline (DPD) levels'were measured before and at the end of the training period.PTH was- increased by 15.32% (p<0.05), 34.88% (p<0.01) and 20.76% (p<0.05) in SSG, MSG, and CG, respectively The increase observed in $Ca^{2+}$ (p=0.054) and OC (p=0.075) in MSG was nearly significant. The percent change observed in MSG was greater than the change in CG in $Ca^{2+}$ and OC (p<0.05 and p<0.01, respectively). There were no significant differences in phosphate and DPD levels within and between groups.In conclusion the young-adult athletes of the MSG had elevated PTH and OC values, which indicate a better bone mineral metabolism. Thus, resistance training performed in multiple sets can be recommended to increase bone mineral content.