Mustafa Coşan TEREK, Levent AKMAN, Osman ZEKİOĞLU, Yılmaz DİKMEN, Serdar ÖZŞENER, M. Sait YÜCEBİLGİN

Postmenopozal dönemde endometrial hiperplazi nedeni olan overin granülosa hücreli tümörü: Olgu sunumu ve literatür derlemesi

Granülosa hücreli tümör, seks kord stromal kaynaklı, nadir görülen ve sıklıkla östrogen gibi seks steroidleri sentezleyebilen bir over tümörüdür. Bu çalışmada proliferatif endometrium bulunan ve cerrahi sonrası överin granüloza hücreli tümörü saptanan bir olgu sunulmuştur. Yetmiş yaşında postmenopozal uterin kanama nedeniyle başvuran olguda, transvajinal sonografide kalın ve düzensiz endometrium saptanarak endometrial örnekleme yapılmıştır. Histopatoloji sonucunun atipisiz endometrial hiperplazi gelmesi üzerine abdominal total histerektomi ve bilateral salpingooforektomi uygulanan hastada; materyallerin histopatolojik incelenmesi sonucunda sağ överde granulosa hücreli tümör saptanmıştır.

Anahtar Kelimeler:

Endometriyum hiperplazisi, Granüloza hücre tümörü, Yumurtalık neoplazmları, Yumurtalık, Postmenopoz

Granulosa cell tumor of the ovary in a postmenopausal patient with endometrial hyperplasia: Report of a case review of the literature

Granulosa cell tumor of the ovary is one of the sex cord stromal tumors of the ovary and often has the ability to secrete sex steroids such as estrogen. In our article we present a patient who showed proliferative endometrium preoperatively and granulosa cell tumor of ovary after the surgical exploration. We report a 70-year-old patient with postmenopausal vaginal bleeding. We performed endometrial sampling from the patient who had thick and irregular endometrium on transvaginal sonography. The biopsy result was simple endometrial hyperplasia without atypia. We performed a total abdominal hysterectomy and bilateral salpingo-oophorectomy. Histopathological examination of the ovaries revealed a granulosa cell tumor of right ovary.

Keywords:

Endometrial Hyperplasia, Granulosa Cell Tumor, Ovarian Neoplasms, Ovary, Postmenopause,

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