Parotis karsinosarkomu (parotisin gerçek malign miks tümörü): Olgu sunumu

Tükrük bezinin gerçek malign miks tümörleri (karsinosarkomlar), agresif seyirli, karsinomatöz ve sarkomatöz elemanları birarada içeren nadir görülen neoplazmlardır. Bu makalede 54 yaşında sol kulak altında 6 yıldır var olan , son bir yıldır hızla büyüyen kitle nedeniyle hastanemize başvuran ve gerçek malign miks tümör tanısı alan olgu sunuldu. Mikroskopik incelemede pleomorfik adenom alanları ile birarada bulunan spesifiye edilemeyen adenokarsinom alanları izlendi. Ayrıca malign fibröz histiositom benzeri pleomorfik sarkom ağırlıkta olmak üzere kondrosarkom ve liposarkom alanlarından oluşan sarkomatöz komponentin arasında sıkışmış indiferan karsinom alanları mevcuttu. Klinik hikaye ve immunohistokimyasal bulgular tümörün myoepitelyal kökenini kanıtlar nitelikteydi.

Carcinosarcoma (malignant mixed tumor) of parodit gland: A case report

True malignant mixed tumor (carcinosarcoma) of salivary gland is an agressive and extremely rare neoplasm composed of both carcinomatous and sarcomatous elements. We report a case of a ture malignant mixed tumor of the parotid gland in a 54 year old man who had a mass for 6 years which rapidly enlarged for the last 1 year. Microscopic examination showed pleomorphic adenoma in association with not otherwise specified adenocarcinoma, and undifferentiated carcinoma which was intermingled with sarcomatous elements. The latter consisted mainly of malignant fibrous histiocytoma like plemorphic sarcoma, chondrosarcoma and liposarcoma. Clinical history and immunohistochemical findings suggested that the tumor was of myoepithelial cell origin.

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