Overin malign mikst müllerian tümörleri: Üç olgu sunumu

Overin malign mikst müllerian tümörleri (MMMT) nadir görülen, histolojik olarak malign epitelyal ve mezenkimal komponent içeren oldukça agresif neoplazmlardır. Bu tümörler tüm over malignitelerinin %1'inden azını oluşturur ve daha çok düşük pariteli ve postmenapozal kadınlarda görülür. Yapılan çalışmalar en önemli prognostik faktörün tanı konduğu sıradaki klinik evrenin olduğunu vurgulamaktadır. İleri evrelerde olan ilk iki olgumuz takiplerinin ilk bir yılı içinde kaybedilirken evre IA olan üçüncü olgumuz yedi yıldan beri yaşamını sürdürmektedir. Olgu sayımız çok az olmasına rağmen overin MMMT'lerinde evrenin en önemli prognostik faktör olduğu sonucuna vardık.

Ovarian malign mixed mullerian tumors: Report of three cases

Ovarian MMMT is a rare, highly aggressive neoplasm comprising histologically of both epithelial and mesenchymal components. This tumor constitutes less than 1% of all ovarian malignancies and tend to occur in low parity women of postmenapausal status. In recent studies, the most important prognostic factor that has been demostrated is the clinical stage at the time of diagnosis. Although our two patients who were in advanced stages died in one year, the third patient was in stage IA and she is still alive and on follow-up for seven years. Although the number of the cases presented here is small, we demonstrated that the stage was a significant prognostic factor in ovarian MMMT.

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