F. AKERCAN, B. ZEYBEK, E. N TAVMERGEN GOKER, N. KARADADAŞ

Maternal primary CMV infection with fetal transmission

Sitomegalovirus (CMV) insanlardaki en sık konjenital enfeksiyondur. Konjenital CMV enfeksiyonu primer veya tekrarlayan maternal enfeksiyonu takiben gelişebilir ve intrauterin gelişme geriliği, mikrosefali, koryoretinit, sensorinoral işitme kaybı, anemi, trombositopeni, sarılık ve hepatosplenomegali gibi bir veya birden fazla klinik manifestasyona yol açabilir. CMV serokonversiyonu gebe kadınların %1-4' ünde görülür. Olgumuzda, 22. haftada amniotik sıvı PCR analizi ile tanısı konan primer konjenital CMV enfeksiyonunu sunmaktayız.

Fetal geçiş gösteren maternal primer CMV enfeksiyonu

The human cytomegalovirus (CMV) is the most common congenital infection in humans. Congenital CMV infection can follow either a primary or recurrent maternal infection, and it can cause one or more of several clinical manifestations such as intrauterine growth restriction, microcephaly, chorioretinitis, sensorineural hearing loss, anemia, thrombocytopenia, jaundice, and hepatosplenomegaly. Seroconversion to cytomegalovirus occurs in 1-4% of pregnant women. We present the case of a pregnant woman with primary congenital cytomegalovirus infection diagnosed by PCR method of amniotic fluid at the 22nd week of pregnancy.

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