Kondroid lipom: Olgu sunumu
Kondroid lipom, miksoid liposarkom ve iskelet dışı miksoid kondrosarkom patolojik özellikleriyle benzerlik gösteren, nadir bir yağ doku tümörüdür. Bu malign tümörlerin aksine, agresif davranmazlar ve radikal tedavi gerektirmezler. Tümör tipik olarak ekstremitelerin yüzeyel dokularında, iyi sınırlı kitle olarak görülür. Bu çalışma ile sağ el volar yüzde 1. ve 2. metakarp komşuluğunda yerleşmiş bir kondroid lipomun patolojik bulguları sunuldu ve ayırıcı tanı tartışıldı.
Chondroid lipoma: Case report
Chondroid lipoma is a rare tumour of adipose tissue, bearing a strikingly close pathologic resemblance to myxoid liposarcoma and extraskletal myxoid chondrosarcoma. Unlike these malignant tumours, chondroid lipoma has a non-aggressive behaviour and does not require radical treatment. This tumour typically presents as a well-defined mass in the superficial tissues of the extremities. In this study, pathologic findings of chondroid lipoma located volar side of the hand, neighboring 2. and 3 metacarpal bones, was presented and differential diagnosis was discussed.
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- 1. Meis JM, Enzinger FM. Chondroid lipoma. A unique tumor simulating liposarcoma and myxoid chondrosarcoma. Am J Surg Pathol 1993; 17 (11): 1103-1112.
- 2. Logan PM, Janzen DL, O’Connell JX, et al. Chondroid lipoma: MRI appearances with clinical and histologic correlation. Skeletal Radiol 1996; 25: 592-595.
- 3. Boets A, Mieghem I, Sciot R, et al. Chondroid lipoma of the trunk: MRI appearance and pathologic correlation. Skeletal Radiology 2004; May 5.
- 4. Guiliou L, Coindre J-M. Newly described adipocytic lesions. Seminars in Diagnostic Pathology 2001; 18 (4): 238-249.
- 5. Yang YJ, Damron TA, Ambrose JL. Diagnosis of chondroid lipoma by fine-needle aspiration biopsy. Arch Pathol Lab Med 2001; 125: 1224-1226.
- 6. Gisselsson D, Domanski H, Höglund M, et al. Unique cytological features and chromosome aberrations in chondroid lipoma. Am J Surg Pathol 1999; 23 (10): 1300-1304.
- 7. Enzinger FM, Weiss SW: Benign lipomatous tumors. Soft Tissue Tumors.Third edition, St Louis ; Mosby. 1994: 395.
- 8. Kindblom L-G, Meis-Kindblom J-M. Chondroid lipoma: an ultrastructural and immunohistochemical analysis with further observations regarding its differentiation. Human Pathology 1995; 26: 706-715.
- 9. Nielsen GP, O’Connell JX, Dickersin G R, et al. Chondroid lipoma, a tumor of white fat cells. Am J Surg Pathol 1995; 19: 1272-1276.
- 10. Ballaux F, Rychter MD, Wever I, et al. Chondroid lipoma is characterized by t(11;16) (q13;p12-13). Virchows Arch 2004; 444: 208-210.
- 11. Enzinger FM, Shiraki M. Extraskeletal myxoid chondrosarcoma. An analysis of 34 cases. Hum Pathol 1972; 3: 421-435.
- 12. Meis-Kindblom JM, Bergh P, Gunterberg B, et al. Extraskeletal myxoid chondrosarcoma: A reapprasial of its morphologic spectrum and prognostic factors based on 117 cases. Am J Surg Pathol 1999; 23: 636-650.
- 13. Kilpatrick SE, Hitchcock MG, Kraus MD, et al. Mixed tumors and myoepiteliomas of soft tissue: a clinicopathologic study of 19 cases with a unifying concept. Am J Surg Pathol 1997; 21: 13-22.
- 14. Michal M, Miettinen M. Myoepitheliomas of the skin and soft tissues. Report of 12 cases. Virchows Arch 1999; 434 (5): 393-400.
- 15. Folpe AL, Agoff SN, Willis J, et al. Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma. Am J Surg Pathol 1999; 23(9): 1059-1067.
- 16. Fisher C, Miettinen M. Parachordoma: a clinicopathologic and immunohistochemical study of four cases of an unusual soft tissue neoplasm. Ann. Diagn Pathol 1997;1(1):3-10.