Işıl KILINÇ, Can CEYLAN, İdil ÜNAL, Fezal ÖZDEMİR, Sibel ALPER

Jeneralize pruritus ve sistemik hastalıklar: Bir retrospektif çalışma

Primer deri bulgusu olmaksızın jeneralize pruritus, kolestaz, üremi, malign, hematolojik, endokrin ve metabolik hastalıklar gibi birçok hastalığın belirtisi olabilmektedir. Çalışmamızda, Ege Üniversitesi Tıp Fakültesi Dermatoloji Anabilim Dalı'nda Ocak 1996- Ocak 2001 yılları arasında jeneralize pruritus nedeni ile hospitalize edilen 50 olgu ilişkili olabileceği hastalıklar açısından retrospektif olarak değerlendirildi. Onbir (%22) hastada diabetes mellitus, 13 (%26) hastada emosyonel stres ve psikiyatrik hastalık, 9 (%18) hastada anemi, 4 (%8) hastada kronik böbrek yetmezliği, 3 (%6) hastada tiroid hastalığı, 2 (%4) hastada Hodgkin lenfoma, 2 (%4) hastada kronik hepatit C enfeksiyonu saptandı. Dermatolojik olarak değerlendirildiğinde ise pruritusa, 20 (%40) hastada mikotik enfeksiyonlar, 10 (%20) hastada da kserozis eşlik etmekteydi. Pruritus yakınma süreleri ile birliktelik saptanan hastalıklar arasındaki ilişki istatistiksel olarak değerlendirildi.

Anahtar Kelimeler:

Araştırma teknikleri, Geriyedönük çalışma, Kaşıntı

Generalized pruritus and systemic diseases: A retrospective study

Generalized pruritus without primary skin manifestations may be the presenting symptom of cholestasis, uremia, malignant, hematologic, endocrine, and metabolic diseases. In this study, 50 cases of generalized pruritus, who were followed up in Ege University Medical Faculty Dermatology Clinic between January 1996 - January 2001, was evaluated to determine the incidence of associated systemic diseases retrospectively. Eleven cases (%22) of diabetes mellitus, 13 (%26) cases wtih emotional stress and psychiatric diseases, 9 (%18) cases of anemia, 4 (%8) cases of chronic renal failure, 3 (%6) cases of thyroid diseases, 2 (%4) cases of Hodgkin lymphoma, and 2 (%4) cases of chronic hepatitis C infection accompanied the pruritus. Dermatological examination revealed 20 (%40) cases with mycotic infections and 10 (%20) cases with xerosis. The relation between the duration of generalized pruritus and associated systemic diseases was evaluated statistically.

Keywords:

Investigative Techniques, Retrospective Studies, Pruritus,

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