M. KARAKUŞ, Derici Yeşer KARACA, Ş GÜNÇİNER

Gebelerde grup B streptokok kolonizasyonu ve antimikrobiyal direnç paterni

Bu çalısma grup B streptokokların (GBS) anne ve yenidoğan enfeksiyonlarındaki önemi dikkate alınarak üçüncü trimestr gebelerde GBS kolonizasyon oranını ve antimikrobiyal direnç profilini belirlemek amacıyla yapıldı. Gereç Yöntem: Bu prospektif çalısmada üç aylık süre içinde üçüncü trimestrdeki 112 gebeden vaginal, rektal ve üretral sürüntü örnekleri alındı. Bulgular : Toplam kolonizasyon oranı %8, vaginal kolonizasyon oranı %2.6 olarak saptandı. Hiçbir kökende penisilin, klindamisin, azitromisin, seftriakson, sefazolin, sefotaksim direnci saptanmazken kökenlerin tamamı tetrasikline dirençli bulunmustur. Tartısma : Sonuç olarak hamilelerin GBS tasıyıcılığı yönünden taranması ve antimikrobial direnç paterninin arastırılmasının intrapartum profilaksiye yön vermek açısından önemli olduğunu düsünmekteyiz.

Anahtar Kelimeler:

Gebelik, İleriye dönük çalışma, Mikrobiyal duyarlılık testleri, Streptococcus agalactiae, İlaç direnci, mikrobiyal

Colonization and antimicrobial resistance patern of group B streptococcus in pregnant women

: The aim of this study was to determine the prevalance of group B streptococcus (GBS) colonization and to evaluate the antimicrobial resistance patern in the third term pregnants in respect to the importance of maternal and neonatal GBS infections. Materials and Methods: In this prospective study over a tree-months period 112 third term pregnant women were screened for GBS colonization. Samples were collected from the vagina, rectum and the urethra. Results: The overall maternal carriage rate was found to be %8 while vaginal colonization rate was %2.6. All of the isolates were sensitive to penicillin, clindamycin, azithromycin, cephazoline, cefotaxime and ceftriaxone whereas all were resistant to tetracycline. Conclusion : In conclusion, screening and evaluation of antimicrobial susceptibility testing of GBS during pregnancy is important to guide appropriate intrapartum prophylaxis.

Keywords:

Pregnancy, Prospective Studies, Microbial Sensitivity Tests, Streptococcus agalactiae, Drug Resistance, Microbial,

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