Deniz ÖZTEKİN, SEFA KURT, Şivekar TINAR, Onur KARALTI, Hakan CAMUZCUOĞLU, Sevil SAYHAN, Özgür ÖZTEKİN

Epitelial ovaryum kanserlerine eşilk eden ovaryan endometriozis

Amaç : Bu çalışmayı endometriyozis ile ovaryum kanseri arasındaki ilişkiyi araştırmak için planladık. Bulduğumuz sonuçlarla birlikte benign bir hastalık olarak kabul edilen endometriozise yaklaşımımızı yeniden değerlendirmeyi amaçladık. Gereç - Yöntem : Ocak 1998 - Aralık 2003 tarihleri arasında hastanemiz onkoloji bölümünde ovaryum karsinomu nedeni ile ameliyat edilen 322 hastanın dosyaları retrospektif olarak incelendi. Postoperatif patoloji raporunda malign ovaryum tümörü ile birlikte endometriozis saptanan 13 olgu çalışmaya alındı. İstatistiksel analiz için SPSS for Windows 10.0 bilgisayar programı kullanıldı. Çalışmanın verileri t testi kullanılarak değerlendirildi ve sağ kalım analizi için kaplan-maier yöntemi seçildi. Bulgular: Hastaların ortalama yaşı 47.53±7.57 (38 - 68) olup, 3 olgu menopozdaydı.5 hastada berrak hücreli tümör, 4 hastada endometrioid tümör, 2 si borderline olmak üzere 3 hastada seröz tümör, 1 hastada granüloza hücreli tümör endometriozis ile birlikteydi. Hastaların 5 yıllık sağ kalım oranı %83.08 olarak hesaplandı. Olguların erken evrede fark edilebilmesi sağ kalımda avantaj oluşturmasına karşın (% 76. 92) en sık birlikte izlenen ovaryum tümörünün berrak hücreli tip (%38.46) olması bu avantajı sınırlamaktadır. Sonuç : Endometriozis ile birlikte olan ovaryum tümörlerinin 5 yıllık yaşam şansı endometriozis ile birlikte olmayanlardan daha iyidir.

Anahtar Kelimeler:

Yumurtalık neoplazmları, Endometriyoz, Geriyedönük çalışma

Ovarian endometriosis with epithelial endometriosis

Objective: We planned this study to search the relationship between endometriosis and ovarian cancer. The aim of the study is to reanalyse our approach to endometriosis which is known as a benign condition. Materials-Methods: We have searched retrospectively the files of 322 patients who had been operated for ovarian carcinoma in oncology department of our hospital, between January 1998 and December 2004. The13 patients in whom endometriozis was found concommittantly with a malign ovarian tumor during surgery, were included in the study. Statistical analysis were done by SPSS for Windows 10.0. Student t test and Kaplan-maier survival analysis were used for calculations. Results: The mean age of patients was 47.53±7.57(38-68). Three of them were in postmenoposal period. Five of the patients had clear cell carcinoma, four had endometrioid carcinoma, three had serous cystadenocarcinoma and while only oneofthem had granulosa cell carcinoma. Five years survival rate was %83.08. Conclusions: Although detection of the cases in early stages due to signs and symptoms of endometriosis was an advantage for survival (76.92%), this advantage has been limited due to the fact that the most common concommittant tumor was clear cell carcinoma (38.46%). Conclusion: The 5 years survival rates are better for concommittant tumors than tumors without endometriosis.

Keywords:

Ovarian Neoplasms, Endometriosis, Retrospective Studies,

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