Ege Üniversitesi Tıp Fakültesi veri tabanındaki kolorektal kanserli olguların epidemiyolojik ve genel sağ kalım özellikleri

Amaç: Kolorektal kanser (KRK) epidemiyolojisi ve genel sağ kalım (GSK) özelliklerinin araştırılmasıdır. Gereç ve Yöntem: Ege Üniversitesi Kanserle Savaş Uygulama ve Araştırma Merkezine (EÜKAM) 1992-2017 yıllarında kayıtlı Ege Üniversitesi Tıp Fakültesi kanser verileri retrospektif olarak taranmıştır. CANREG özel bilgisayar programına kayıtlı veriler, WHO ve SEER sistemlerinde gruplanarak analizler yapılmıştır. İstatistiksel analizlerde Ki-kare, General Linear Model (GLM), Kaplan-Meier sağ kalım analizleri kullanılmıştır. Yerel etik kurul onayı alınmıştır. Bulgular: Toplam 117.139 kanser olgusunun 7.285‟i (%6,2) KRK‟dir. KRK sıklığı, tüm olgular içinde yedinci sırada saptanmıştır. Olguların 4.330‟u (%59) erkektir. Rektum yerleşimi, %38,4 olguda saptanmış olup, en sık lokalizasyondur. KRK yaşla artmaktadır; 60 yaş ve üzerinde her iki cinsiyette de anlamlı artış saptanmıştır (p=0,022); cinsiyetler arası fark anlamlı değildir (p=0,299). KRK‟de yıllara göre doğrusal artış toplamda anlamlıdır (GLM: F=12,349; p

Epidemiologic and survival characteristics of patients with colorectal cancer in Ege University medical faculty database

Aim: The aim of this study was to determine epidemiological and overall survival (OS) characteristics of colorectal cancer (CRC) patients. Materials and Methods: Data of Ege University Cancer Control and Research Center between 1992- 2017 were screened retrospectively. Data recorded in CANREG program were grouped and analyzed in WHO and SEER systems. Chi-square test, General Linear Model (GLM) and Kaplan-Meier survival analysis were used for statistical analysis. Results: Number of CRC cases were 7285 (6.2%) among 117139 cancer cases. CRC ranked 7th among all the cancer types. Of the CRC patients, 4330 (59%) were male. The most common localization was rectum (38.4%). CRC increases with age. A significant increase was found at the age of 60 years and older (p=0.022) among both genders, but the difference between genders was not significant (p=0.299). Linear increase over the years was significant in total (GLM: F=12,349; p

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