Amaç: Bu çalışmanın amacı, Ege Üniversitesi Tıp Fakültesi Hastanesi veri tabanında bulunan, merkezi sinir sistemi (MSS) tümörü tanısı ile tedavi edilen 5877 adet olgunun epidemiyolojik ve genel sağ kalım özelliklerini istatistiksel açıdan değerlendirmek ve literatür ile karşılaştırmaktır. Gereç ve Yöntem: 1992 ile 2017 yılları arasında Ege Üniversitesi Tıp Fakültesi Hastanesinde tanı alan 5877 adet MSS kanseri olgusu, Ege Üniversitesi Kanserle Savaş, Uygulama ve Araştırma Merkezi’nin (EÜKAM) özel eğitimli ve sertifikalı kanser kayıt elemanları tarafından kayıt altına alınan veriler, Ki-kare testi ve doğrusal modelleme yöntemi kullanılarak analiz edilmiş, p
Aim: The aim of this study was to evaluate the epidemiological and overall survival characteristics of 5877 patients diagnosed with Central Nervous System tumors in the database of Ege University Faculty of Medicine and compare them with the literature. Materials and Methods: 5877 cases of CNS cancer diagnosed at Ege University Hospital between 1992 and 2017 were recorded by specially trained and certified cancer registry staff of Ege University Cancer Control, Application and Research Center(EUCRC) analyzed using linear modeling method and Chi-Square test and p
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1. Louis D. N., Ohgaki H., Wiestler O. D., et al. "The 2007 WHO classification of tumours of the central nervous system." Acta neuropathologica 2007;114.2.: 97-109.
2. Percy C., Holten V. V., Muir C. S., et al. "International classification of diseases for oncology." 1990.
3. Ostrom Q. T., Gittleman H., Farah P., et al. "CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2006-2010." Neuro-oncology 15.suppl_2. 2013: ii1-ii56.
4. Lee C. H., Jung K. W., Yoo H., et al. "Epidemiology of primary brain and central nervous system tumors in Korea." Journal of Korean Neurosurgical Society 2010;48. 2: 145.
5. Polednak A P. "Interpretation of secular increases in incidence rates for primary brain cancer in Connecticut adults, 1965–1988." Neuroepidemiology 1996;15.1: 51-6.
6. Ostrom Q. T., Gittleman H., Truitt G., et al. "CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2011–2015." Neuro-oncology 20.suppl. 2018;4: iv1-iv86.
7. Ferlay J., Ervik M., Lam F., et al. ‘’Global cancer observatory: Cancer today.’’ Lyon: International Agency for Research on Cancer; 2018.
8. Bray F., Ferlay J, Soerjomataram I, et al. ‘’Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.’’ CA Cancer J Clin 68: 394-324, 2018
9. Custer B., Longstreth W. T., Phillip, L. E., et al. "Hormonal exposures and the risk of intracranial meningioma in women: a population-based case-control study." BMC cancer 6.1 (2006): 152.
10. Miranda-Filho A., Piñeros M., Soerjomataram I., et al. ‘’Cancers of the brain and CNS: Global patterns and trends in incidence.’’ Neuro-oncology 19(2):270-280, 2016
11. llemani C., Matsuda T., Di Carlo V., et al. ‘’CONCORD Working Group: Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): Analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.’’ Lancet 391 (10125): 1023-1075, 2018
12. Lin D. D., Lin J. L., Deng X. Y., et al. "Trends in intracranial meningioma incidence in the United States, 2004‐ 2015." Cancer medicine 8.14 (2019): 6458-67.
13. Brodbelt A. R., Barclay M. E., Greenberg D., et al. "The outcome of patients with surgically treated meningioma in England: 1999–2013. A cancer registry data analysis." British journal of neurosurgery (2019): 1-7.
14. Wrensch M., Minn Y., Chew T., et al. ‘’Epidemiology of primary brain tumors: Current concepts and review of the literature.’’ Neuro-oncology 4 (4): 278-99.
15. Sencan İ., Keskinkilic B. ‘’Türkiye kanser istatistikleri’’ Ankara: T.C. Sağlık Bakanlığı Türkiye Halk Sağlığı Kurumu, 2017.