Nurşen KÖMÜRCÜLÜ, Ebru BAKAR, Hatice MAVİOĞLU

Akrep sokması ve immun serum-tetanus aşısı uygulaması sonrasında gelişen bir akut sensori-motor polinöropati olgusu

Hayvan sokmalarında uygulanan serum ve toksinler immunojenik ajanlardır. Akut enflamatuar polinöropatiyi de içeren bir dizi immun nörolojik hastalığa neden olabilirler. 43 yaşında erkek olgu, akrep tarafından sokulma ve akrep serumu ile tetanus aşısı uygulamasından 10 gün sonra ortaya çıkan ekstremitelerde parestezi ve güçsüzlük yakınması ile başvurdu. Olguya klinik ve laboratuvar bulguları ile akut sensorimotor polinöropati tanısı konuldu. IVIG tedavisi uygulandı ve klinik bulgular geriledi. Akut sensorimotor polinöropati'nin olaydan 10 gün sonra ortaya çıkması nedeni ile bu tablonun toksine değil, akrep serumu ya da tetanus aşısının oluşturduğu immun yanıta bağlı olduğu düşünüldü. Akrep serumu uygulaması sonrası bildirilen hiçbir polinöropati olgusunun olmaması ve tetanus aşısından sonra da çok nadir görülmesi nedeni ile olgu sunulmaya değer bulundu.

Anahtar Kelimeler:

Akrep zehirleri, Serum, Orta yaşlı, Erkek, Böcek ısırma ve sokmaları, Guillain-Barre sendromu, Tetanos toksoidi, Polinöropatiler

An acute sensorimotor polyneuropathy case after scorpion sting and administration of immune serume-tetanus vaccine

Serum and toxins used in animal stings are immunogenic agents. They can cause multiple immune neurologic disease including inflammatory polyneuropathy. Forty three years old male were. He referred with the symptoms of paresthesia and weakness of extremities 10 days after the scorpion sting and tetanus vaccine and scorpion serum had been administered. Acute sensorimotor polyneuropathy was diagnosed with clinical and laboratory findings. After IVIG treatment the clinical findings improved. Due to the fact that Acute sensorimotor polyneuropathy appeared 10 days after the event, it was thought that the situation was dependent on immune response, which had been created by scorpion serum and tetanus vaccine, but not by toxins. Since there is no polyneuropathy case reported after scorpion serum administration and it is very rarely associated with the vaccine, we think the case is valuable for presenting.

Keywords:

Scorpion Venoms, Serum, Middle Aged, Male, Insect Bites and Stings, Guillain-Barre Syndrome, Tetanus Toxoid, Polyneuropathies,

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