The efficiency of hemodialysis in transfusion-related acute lung injury (TRALI): A case report

Transfusion-Related Acute Lung Injury (TRALI) is an important life-threatening complication that is related with blood transfusion. The frequency is reported as 1/5.000. It is generally characterized with hypoxia that appears at the 2-6th hours after the blood transfusion, bilateral infiltration in the chest radiography, and non-cardiogenic pulmonary edema. Acute respiratory distress, hypotension, tachycardia and fever accompany the clinical picture. Past surgery, blood transfusion, and sepsis are among the factors that trigger the disease. In this study, the efficiency of the hemodialysis applied in the right time in the treatment of a heavy TRALI case developed after a blood transfusion has been presented.

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1. Bux J, Ulrich JH. Sachs. The pathogenesis of transfusion-related acute lung injury (TRALI). British Journal of Haematology 2007; 136: 788-799.

2. Chu LF, Fuller AJ. Çeviri: Turkan M. Kan ürünleri tedavisi. In: Klinik anesteziyoloji el kitabi. Çeviri Ed: Özcengiz D, Birbiçer H, Inanoglu K, Oksuz H, Ganidagli S. Ankara: Akademisyen 2014: 209-214.

3. Bolaman Z, Camci C, Sönmez HM, et al. High Dose Methylprednisolone Treatment of Transfusion Related Acute Lung Injury: Case Report. ADÜ Tip Fak. Dergisi 2000; 1: 43-46.

4. Bas T, Malbora B, Capanoglu M, Isik O, Kutsal A. Recurrent transfusion-related acute lung injury after open heart surgery: a case report. Türk Gögüs Kalp Damar Cerrahisi Dergisi 2013; 21: 483-486.

5. Kopko PM, Popovsky MA, MacKenzie MR, et al. HLA class II antibodies in transfusionrelated acute lung injury. Transfusion 2001; 41: 1244-1248.

6. McKenzie CG, Kim M, Singh TK, et al. Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI). Blood 2014; 123: 3496-3503.

7. Silliman CC, Boshkov LK, Mehdizadehkashi Z, et al. Transfusion-related acute lung injury: epidemiology and a prospective analysis of etiologic factors. Blood 2003; 101: 454-462.

8. Gunay C, Cingoz F, Sahin MA, et al. Transfusion related acute lung injury after open heart surgery. Gulhane Med J 2008; 50: 131-133.

9. Besisik SK, Karahan G, Oztürk G, et al. Transfusion related acute lung injury. Nobel Med 2011; 7: 110-113.

10. Holness L, Knippen MA, Simmons L, Lachenbruch PA. Fatalities caused by TRALI. Transfusion Medicine Reviews 2004; 18: 184-188.

11. Popovsky MA, Moore SB. Diagnostic and pathogenetic considerations in transfusion-related acute lung injury. Transfusion 1985; 25: 573-577.