Farah Dayana ZAHEDİ1, Mohd Hazmi MOHAMED, Salina HUSAİN1, Thean Yean KEW, Balwant Singh GENDEH

Clinical and radiological impact markers in evaluating characteristic unilateral paranasal sinus diseases

The study was aimed to analyze the clinical and radiological features, which characterized specific unilateral sinus diseases. A retrospective review of patients’ medical records with unilateral sinus opacification detected from computed tomography (CT) scan for 10 years duration in UniversitiKebangsaan Malaysia Medical Centre (UKMMC). The clinical presentation, mean age, presence of calcification and bony destruction and Lund Mackay scor e between groups were compared. Total of 151 (23.5%) patients had unilateral paranasal sinus opacification on CT scan from 640 scan reviewed with 99 (65.6%) had inflammatory diseases, 38 (25.2%) had benign neoplastic condition and 14 (9.3%) with malignant neoplastic condition. Epistaxis was found to be significantly higher in malignant group (n=12/14) while rhinorrhea was higher in inflammatory condition (n=65/99). Bone erosion and mean Lund Mackay score were higher in malignant neoplasms group Computed tomography imaging combined with clinical presentation can be used as a tool to suspect malignant sinonasal disease. One should be highly suspicious of malignancy if the Lund-Mackay score of the CT paranasal sinus is high. However, tissue biopsy is still needed for confirmation.

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