SEVDA KORKMAZ, Hasan KORKMAZ, Murad ATMACA, Murat KULOĞLU

Sitalopram ile suisid girişimi sonrasında sinüs ritminin baskılanarak atrial ritmin geliştiği bir olgu

Selektif serotonin geri alım inhibitörleri (SSRI), norepinefrin veya dopamin geri alımını etkilemeden, presinaptik alanda serotonin geri alımını inhibe eden, etkili ve oldukça güvenli olarak bilinen antidepresan ilaçlardır. Bununla beraber, SSRI’lar da dahil, tüm antidepresan ilaçların yüksek dozda kullanımlarına bağlı olarak merkezi sinir sistemi, solunum sistemi ve kardiyovasküler sistemde birtakım toksik etkiler gözlenebilmektedir. Yazımızda, bir SSRI olan sitalopramın yüksek dozlarda alınmasıyla EKG’de bazı değişiklikler gözlemlediğimiz bir olgu sunulacaktır.

A case of a suicide attempt with sitalopram causing supression of sinusal rhythm with development of atrial rhythm

Selective serotonine reuptake inhibitors (SSRI) are known as effective and quite safe antidepressant drugs which inhibit seratonin reuptake in the presynaptic area without affecting the noradrenaline and dopamine reuptake. Nevertheless, in high dose use of all antidepressants, including SSRI, some toxic effects might be observed in central nervous system, respiratory system and cardiovascular system. In our article, we present a case who developed electrocardiographic changes due to use of citalopram in high doses.

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