Pharmacopsychosocial treatment of opioid dependence: Harm reduction, palliation, or simply good medical practice?


1. Koob GF, Le Moal M. Plasticity of reward neurocircuitry and the ‘dark side’ of drug addiction. Nat Neurosci 2005; 8:1442-1444.

2. Chen D, Liu F, Shang Q, Song X, Miao X, Wang Z. Association between polymorphisms of DRD2 and DRD4 and opioid dependence: Evidence from the current studies. Am J Med Genet B Neuropsychiatr Genet 2011; 156:661-670.

3. Weiss RD, Potter JS, Fiellin DA, Byrne M, Connery HS, Dickinson W, Gardin J, Griffin ML, Gourevitch MN, Haller DL, Hasson AL, Huang Z, Jacobs P, Kosinski AS, Lindblad R, McCance-Katz EF, Provost SE, Selzer J, Somoza EC, Sonne SC, Ling W. Adjunctive Counseling During Brief and Extended Buprenorphine-Naloxone Treatment for Prescription Opioid Dependence: A 2-Phase Randomized Controlled Trial. Arch Gen Psychiatry 2011; 68:1238- 1246.

4. CDC. CDC Grand Rounds: Prescription Drug Overdoses — a U.S. Epidemic. Morbidity and Mortality Weekly (MMWR) 61[01], 10-13. 1-13-0012.

5. Tetrault JM, Fiellin DA. Current and potential pharmacological treatment options for maintenance therapy in opioid-dependent individuals. Drugs 2012; 72:217-228.

6. Braden JB, Sullivan MD, Ray GT, Saunders K, Merrill J, Silverberg MJ, Rutter CM, Weisner C, Banta-Green C, Campbell C, Von Korff M. Trends in long-term opioid therapy for noncancer pain among persons with a history of depression. Gen Hosp Psychiatry 2009; 31:564-570.

7. Kleber HD. Methadone maintenance 4 decades later. JAMA 2008; 300:2303-2305.

8. DuPont RL, McLellan AT, Carr G, Gendel M, Skipper GE. How are addicted physicians treated? A national survey of physician health programs. J Subst Abuse Treat 2009; 37:1-7.

9. Taxman FS, Henderson CE, Belenko S. Organizational context, systems change, and adopting treatment delivery systems in the criminal justice system. Drug Alcohol Depend 2009; 103 (Supp. 1):1-6.

10. Ward J, Hall W, Mattick RP. Role of maintenance treatment in opioid dependence. The Lancet 1999; 353:221-226.

11. Khantzian EJ, Mack JE, Schatzberg AF. Heroin use as an attempt to cope: clinical observations. Am J Psychiatry 1974; 131:160-164.

12. Dackis C, O’Brien C. Neurobiology of addiction: treatment and public policy ramifications. Nat Neurosci 2005; 8:1431-1436.

13. Leshner AI. Addiction is a brain disease, and it matters. Science 1997; 278:45-47.

14. Volkow N, Baler R, Goldstein R. Addiction: Pulling at the neural threads of social behaviors. Neuron 2011; 69:599-602.

15. O’Brien CP. Anticraving medications for relapse prevention: a possible new class of psychoactive medications. Am J Psychiatry 2005; 162:1423-1431.

16. Papaleo F, Ghozland S, Ingallinesi M, Roberts AJ, Koob GF, Contarino A. Disruption of the CRF2 Receptor pathway decreases the somatic expression of opiate withdrawal. Neuropsychopharmacology 2008; 33:2878-2887.

17. Gastfriend DR. Intramuscular extended-release naltrexone: current evidence. Ann N Y Acad Sci 2011; 1216:144-166.

18. Oviedo-Joekes E, Brissette S, Marsh DC, Lauzon P, Guh D, Anis A, Schechter MT. Diacetylmorphine versus methadone for the treatment of opioid addiction. N Engl J Med 2009; 361:777-786.

19. Fudala PJ, Bridge TP, Herbert S, Williford WO, Chiang CN, Jones K, Collins J, Raisch D, Casadonte P, Goldsmith RJ, Ling W, Malkerneker U, McNicholas L, Renner J, Stine S, Tusel D. Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone. N Engl J Med 2003; 349:949-958.

20. Nunes EV, Levin FR. Treatment of co-occurring depression and substance dependence: using meta-analysis to guide clinical recommendations. Psychiatr Ann 2008; 38:730-738.

21. Martin PR, Weinberg BA, Bealer BK. Healing Addiction: An Integrated Pharmacopsychosocial Approach to Treatment. Hoboken, New Jersey: John Wiley & Sons Inc., 2007.

22. McLellan AT, Lewis DC, O’Brien CP, Kleber HD. Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. JAMA 2000; 284:1689-1695.

23. Hettema J, Steele J, Miller WR. Motivational interviewing. Annu Rev Clin Psychol 2004; 1:91-111.

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