Neurobiology, Genetics and Treatment of Alcohol Craving

Alkol aşermesi son 10 yılda, giderek artan bir şekilde, alkol kullanım bozukluklarında önemli bir sorun olarak kabul edilmektedir. Alkol aşermesi ile ilgili yapılan biyolojik çalışmalar, daha çok nörobiyoloji, genetik ve bu durumun farmakolojik tedavisi üzerine odaklanmaktadır. Biz bu yazımızda, reseptör sistemlerinden başlayarak, alkol aşermesinin genetiği ve epigenetiğini gözden geçirdik. Son olarak da, alkol aşermesinde kullanılan ana ilaçlardan başlayarak, alkol aşermesinde kullanılması muhtemel diğer ilaçları ve gelecekteki olası tedavi seçeneklerini açıklamaya çalıştık

Alkol aşermesinin nörobiyolojisi, genetiği ve tedavisi

Alcohol craving has increasingly been considered an important issue in alcohol use disorders in the last decade. Biologic studies on alcohol craving were mainly focused on neurobiology, genetics and pharmacological treatment of this condition. In this report, we started from receptor systems, than we explained genetics and epigenetics of alcohol craving. At last, we described the main drugs currently used in the treatment of alcohol craving. Other potential drugs and future choices for treating alcohol craving were also described

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