Mehmet Erdem MEMETOĞLU, ÖZHAN YALÇIN, Ozan ERBASAN

Kardiyak transplantasyon sonrası siklosporin ve sertralin kullanımı ile ilişkili olabilecek akut psikotik bozukluk: Bir olgu sunumu

Siklosporin, kalp transplantasyonu sonrası immünsupresif tedavide kullanılan temel ilaçlardandır. Siklosporin gibi kalsinörin üzerine baskılayıcı etkileri olan immünsupresif ajanların, özellikle akut dönemlerde psikotik tablolara yol açabildiği bilinmektedir. Bu olgu sunumunda, kardiyak transplantasyon sonrası kronik izlemin 3. yılında, siklosporin ve sertralin kullanımı ile ilişkilendirdiğimiz bir akut psikotik bozukluk olgusunu, hazırlayıcı nedenleri ve tedavi yaklaşımı bağlamında sunmak ve tartışmak istiyoruz.

Acute psychotic disorder after cardiac transplantation possibly associated with cyclosporine and sertraline treatment: a case report

Cyclosporine is one of the main agents used in immunsupressive treatment after cardiac transplantation. Like cyclosporine, immunosuppressive agents targeting calcineurin inhibition, have been associated with psychotic symptoms, especially in the acute administration phase of these drugs. In this case report, we want to present an acute psychotic disorder case that we associated with cyclosporine and sertraline treatment, after 3 years follow up of cardiac transplantation and to discuss this case in the context of preparatory factors and treatment approaches.

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