Liken planuslu olgularda mukoza tutulum sıklığı
inflamatuar mukokutan bir dermatozdur. Literatürde liken planusun mukoza tutulumu sıklığı ile ilgili oldukça değişken veriler bulunmaktadır. Dolayısıyla kliniğimizdeki liken planuslu olgularda mukoza tutulumu sıklığının araştırılması amaçlanmıştır. Gereç ve yöntem: Eylül 2002-Aralık 2006 yılları arasında Dokuz Eylül Üniversitesi Tıp Fakültesi Dermatoloji Bölümü’ne başvuran, klinik ve histopatolojik olarak liken planus tanısı almış 53 olgu oral mukoza ve anogenital mukoza tutulumu açısından retrospektif olarak değerlendirilmiştir. Bulgular: Olguların 34’ünde (%64,2) mukoza yerleşimli liken planus döküleri belirlenmiştir. Dökülerin yerleşimi değerlendirildiğinde; 23 olguda sadece oral, 3 olguda sa¬dece genital, 7 olguda oral + genital, 1 olguda ise oralanal mukoza tutunumu sap-tanmıştır. Sonuç: Liken planuslu olgularda mukoza tutulumunun oldukça sık olması, rutin deribilimsel bakıda oral ve anogenital mukoza muayenesinin önemini vurgulamaktadır.
The prevalance of mucosal involvement in patients with lichen planus
Objective: Lichen planus, which affects 1- 4% of the general population, is an inflammatory mucocutaneous disease. There are fairly variable data in the literature about the prevelance of the mucosal involvement of lichen planus. For this reason, we aimed to evaluate prevalance of mucosal involvement of patients with lichen planus. Material and method: Fifty-three patients, who applied to Dokuz Eylül University Hospital’s Dermatology Department between September 2002 and December 2007, were diagnosed lichen planus clinically and pathologically and they were retrospectively evaluated for oral and anogenital mucosal involvement. Results: Mucous membrane involvement was seen in 34 (64,2%) patients. The assesment of the localisation of the lesions was; 23 patients only oral, 3 patients only genital, 7 patients oral and genital both, 1 patient oral and anal mucous membrane both. Conclusion: The fact that the mucosal involvement is very common in patients who have lichen planus emphasizes the importance of routine examination of oral and anogenital mucosae.
___
- 1. Katta R. Lichen planus. Am Fam Physician 2000; 61: 3319-3324.
- 2. Mollaoglu N. Oral lichen planus: a review. Br J Oral Maxillofacial Surgery 2000; 38: 370–377.
- 3. Dissemond J. Oral lichen planus: an overview. J Der-matol Treat 2004; 15: 136–140.
- 4. Moyal-Barracco M, Edwards L. Diagnosis and therapy of anogenital lichen planus. Dermatol Therapy 2004; 17: 38-46.
- 5. Eisen D. The evaluation of cutaneos, genital, scalp, nail, esophageal, and ocular involvement in patients with oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88: 431-436.
- 6. Setterfield JF, Black MM, Challcombe SJ. The mana-gement of oral lichen planus. Clin Exp Dermatol 2000; 25: 176-182.
- 7. Boyd AS, Neldner KH. Lichen planus. J Am Acad Der-matol 1991; 25: 593-619.
- 8. Eisen D, Carrozzo M, Sebastian J-V Bagan, Thongprason K. Oral lichen planus: clinical features and management. Oral Dis 2005; 11: 338-349.
- 9. Kirstchig G, Wakelin SH, Wojnarowska F. Mucosal vulval lichen planus: outcome, clinical and laboratory features. J Eur Acad Dermatol Venereol 2005; 19: 301-307.
- 10. Ingafou M, Leao JC, Porter SR, Scully C. Oral lichen planus: a retrospective study of 690 British patients. Oral Dis 2006; 12: 463-468.
- 11. Marshman G. Lichen planus. Austr J Dermatol 1998; 39: 1-13.
- 12. Bhattacharya M, Kaur I, Kumar B. Lichen Planus: A clinical and epidemiological study. J Dermatol 2000; 27: 576-582.
- 13. Bermejo A, Bermejo MD, Roman P et al. Lichen planus with simultaneous involvement of the oral cavity and genitalia. Oral Surg Oral Med Oral Pathol 1990; 69: 209-216.
- 14. Edwards L. Vulvar Lichen planus. Arch Dermatol 1989; 125: 1677-1680.