Arzu PALANTÖKEN, MÜGE SARI YILMAZ, MELDA ALTIKATOĞLU YAPAÖZ, Sabriye PİŞKİN

INVESTIGATION OF ANTIMICROBIAL PROPERTIES OF HYDROGELS CONTAINING METAL AND METALOXIDE NANOPARTICLES

Bu çalışmada, antibakteriyel aktivitelerini araştırmak için sentezlenmiş TiO2, ticari TiO2 (21 nm), TiO2 (<100 nm), Ag (<100 nm) ve ZnO (<50 nm) nanopartiküllerini içeren hidrojeller hazırlanmıştır. Metal ve metaloksit nanopartikülleri içeren hidrojellerin karakterizasyonları Termogravimetri (TGA) ve Fourier Dönüşümlü Infrared Spektroskopisi (FTIR) analizleri gerçekleştirilmiştir. Bu hidrojellerin, Escherichia coli (E. coli) ve Staphylococcus aureus (S. aureus)’a karşı antibakteriyel aktiviteleri airborne testi ve modifiye edilmiş Kirby Bauer disk difüzyon metotları ile ölçülmüştür. Sonuç olarak, sentezlenmiş TiO2, ticari Ag (<100 nm) ve ZnO (<50 nm) nanopartiküllerini içeren hidrojellerin antibakteriyel aktivitesinin varlığı gösterilmiştir

Anahtar Kelimeler:

Metal ve metaloksit nanopartikülleri (NPs), antimikrobiyal hidrojel, E. coli, S.aureus

METAL VE METALOKSİT NANOPARTİKÜLLERİNİ İÇEREN HİDROJELLERİN ANTİMİKROBİYAL ÖZELLİKLERİNİN İNCELENMESİ

In the present study, we prepared hydrogels containing synthesized TiO2, commercial TiO2 (21 nm), TiO2 (<100 nm), Ag (<100 nm) and ZnO (<50 nm) nanoparticles to investigate the antibacterial properties of these hydrogels. TiO2, Ag and ZnO containing hygrogels were characterized using Thermogravimetry (TGA) and Fourier Transform Infrared Spectroscopy (FTIR) analysis. The antibacterial activities of the hydrogels against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were measured by the airborne testing and modified Kirby Bauer disk diffusion methods. Finally, we demonstrated the presence of antibacterial activity in the hydrogels containing synthesized TiO2, commercial Ag (<100 nm) and ZnO (<50 nm) nanoparticles

Keywords:

Metal and metaloxide nanoparticles (NPs), antimicrobial hydrogel, E.coli, S.aureus,

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